Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264650 | 0.88 | DHODH (0.34) | ADADHODHSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7263018 | 0.81 | ADA (0.41) | ADASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL7258747 | 0.79 | ADA (0.39) | ADADHODHSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7258881 | 0.79 | ADA (0.39) | ADADYRK3MAP4K4PIM1RPS6KB1 | |
| SCHEMBL5671343 | 0.79 | ADA (0.68) | ADA | |
| SCHEMBL7258788 | 0.79 | CHEK2 (0.39) | ADASMN1; SMN2MAPTDYRK3MAP4K4 | |
| SCHEMBL7448841 | 0.78 | ALDH1A1 (0.42) | ADASMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7258984 | 0.78 | CHEK2 (0.41) | ADAMKNK2CHEK2SCN9ACHEK1 | |
| SCHEMBL7264346 | 0.76 | ATP4A (0.38) | ADASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL7259601 | 0.75 | ADA (0.44) | ADASMN1; SMN2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |