Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ADA | P00813 | 5/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453012 | 0.90 | ADA (0.48) | PPARGPPARAADAMRGPRX4ALDH1A1 | |
| SCHEMBL7263602 | 0.85 | PPARG (0.41) | PPARGPPARAADAALDH1A1KDM4E | |
| SCHEMBL7258926 | 0.85 | MRGPRX4 (0.44) | PPARGPPARAADAMRGPRX4 | |
| SCHEMBL7258942 | 0.84 | ADA (0.43) | ATMADAALDH1A1KDM4ELMNA | |
| SCHEMBL7259591 | 0.84 | LMNA (0.42) | ADAALDH1A1LMNA | |
| SCHEMBL7264016 | 0.84 | MCHR1 (0.40) | ADAALOX5 | |
| SCHEMBL7263300 | 0.83 | PDE10A (0.39) | ADACYP2C9KMT2A | |
| SCHEMBL7448692 | 0.81 | ADA (0.38) | ADAALDH1A1KDM4ELMNAALOX5 | |
| SCHEMBL7449720 | 0.81 | SLC1A3 (0.35) | ADAALDH1A1ALOX5CYP2C9MEN1 | |
| SCHEMBL7448884 | 0.81 | SLC6A2 (0.38) | PPARGPPARAADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |