Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258926 | 0.92 | MRGPRX4 (0.44) | ADAPPARGPPARAPPARDXIAP | |
| SCHEMBL7263602 | 0.91 | PPARG (0.41) | ADAPPARGPPARAALOX5KDM4E | |
| SCHEMBL7258752 | 0.90 | ATM (0.41) | ADAPPARGPPARAALOX5KDM4E | |
| SCHEMBL7264016 | 0.86 | MCHR1 (0.40) | ADAALOX5 | |
| SCHEMBL7259591 | 0.86 | LMNA (0.42) | ADAALDH1A1MAPT | |
| SCHEMBL7263300 | 0.86 | PDE10A (0.39) | ADAKMT2AMAPT | |
| SCHEMBL7449954 | 0.84 | KMT2A (0.39) | KDM4EALDH1A1XIAPMEN1POLB | |
| SCHEMBL7448692 | 0.83 | ADA (0.38) | ADAALOX5KDM4EALDH1A1MEN1 | |
| SCHEMBL7449720 | 0.83 | SLC1A3 (0.35) | ADAALOX5ALDH1A1MEN1KMT2A | |
| SCHEMBL7453359 | 0.82 | PDE4A (0.37) | ADAPPARGPPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001026605-A2 | IMMUNOSUPPRESSIVE COMPOSITION CONTAINING IL-2 INHIBITOR AND AN ADENOSINE DEAMINASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-19 | — | — | WO | disclosed |