Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | ADA | P00813 | 5/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263874 | 0.87 | ADA (0.43) | MCHR1ADAS1PR1S1PR3PTGES | |
| SCHEMBL7453012 | 0.86 | ADA (0.48) | ADAALOX5 | |
| SCHEMBL7258752 | 0.84 | ATM (0.41) | ADAALOX5 | |
| SCHEMBL7263602 | 0.82 | PPARG (0.41) | ADAALOX5 | |
| SCHEMBL7258926 | 0.81 | MRGPRX4 (0.44) | ADALNPEP | |
| SCHEMBL7259591 | 0.81 | LMNA (0.42) | MCHR1ADA | |
| SCHEMBL7263300 | 0.80 | PDE10A (0.39) | ADA | |
| SCHEMBL5673392 | 0.79 | ADA (0.55) | MCHR1SLC1A3SLC1A2SLC1A1ADA | |
| SCHEMBL7548118 | 0.78 | MMP9 (0.32) | SLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL7448692 | 0.78 | ADA (0.38) | SLC1A3SLC1A2SLC1A1ADAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |