Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 4/20 | 0.40 |
| ▸ | G6PD | P11413 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258759 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HAO1PAMKMT2AFBP1 | |
| SCHEMBL8697236 | 0.82 | KMT2A (0.41) | ALDH1A1HAO1KMT2AFBP1G6PD | |
| SCHEMBL8697794 | 0.80 | CES1 (0.47) | ALDH1A1HAO1KMT2APOLBGAA | |
| SCHEMBL7227352 | 0.77 | KMT2A (0.47) | ALDH1A1HAO1KMT2AFBP1TDP1 | |
| SCHEMBL7227347 | 0.77 | KMT2A (0.47) | ALDH1A1HAO1KMT2AFBP1TDP1 | |
| SCHEMBL14617615 | 0.76 | G6PD (0.45) | ALDH1A1HAO1KMT2AFBP1G6PD | |
| SCHEMBL1404270 | 0.72 | G6PD (0.42) | ALDH1A1HAO1KMT2AFBP1G6PD | |
| SCHEMBL8699062 | 0.72 | FBP1 (0.41) | ALDH1A1HAO1KMT2AFBP1TDP1 | |
| SCHEMBL268060 | 0.71 | BCHE (0.41) | ALDH1A1HAO1KMT2AFBP1G6PD | |
| SCHEMBL14575602 | 0.71 | G6PD (0.41) | ALDH1A1HAO1KMT2AFBP1G6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003020709-A1 | 1,2-OXAZIN-3-ONE DERIVATIVES AS ANTIBACTERIAL AGENTS | SIMON FRASER UNIVERSITY (CA) | 2003-03-13 | — | — | WO | disclosed |