SCHEMBL7258983

SCHEMBL7258983

C=CC(=O)NC1(S(=O)(=O)O)CC1C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23425000 0.66 TSHR (0.32) TSHR
SCHEMBL38654076 0.65 TGM2 (0.42) TGM2ZDHHC20ZDHHC2TSHR
SCHEMBL27469666 0.65 TGM2 (0.42) TGM2ZDHHC20ZDHHC2TSHR
SCHEMBL24012425 0.64 TSHR (0.31) TSHR
SCHEMBL19019111 0.62
SCHEMBL1070205 0.62 EPHX2 (0.59)
Acrylic Acid SCHEMBL4644611 0.61 LMNA (0.62) TGM2ZDHHC20ZDHHC2TSHR
Sulfuric Acid SCHEMBL27873789 0.61 TSHR (0.42) TGM2ZDHHC20ZDHHC2TSHR
SCHEMBL5197727 0.61
SCHEMBL6232628 0.60 EPHX2 (0.38) TGM2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6645476-B1 Preparable by free-radical copolymerization of macromonomers containing an end-group capable of polymerization, a hydrophilic moiety based on polyalkylene oxides, and a hydrophobic moiety with olefincally unsaturated comonomers CLARIANT GMBH (DE) 2003-11-11 US disclosed