Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.40 |
| ▸ | DRD4 | P21917 | 8/20 | 0.40 |
| ▸ | DRD3 | P35462 | 7/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
| ▸ | CCR3 | P51677 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 7/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328290 | 0.89 | HRH1 (0.44) | DRD2DRD4DRD3HRH1CCR3 | |
| SCHEMBL6334766 | 0.81 | DRD4 (0.44) | DRD2DRD4DRD3KCNH2HTR4 | |
| SCHEMBL6336355 | 0.76 | DRD2 (0.39) | DRD2DRD4DRD3HTR4 | |
| SCHEMBL6327323 | 0.76 | GRIN1 (0.43) | DRD2DRD4DRD3KCNH2HTR4 | |
| SCHEMBL7259547 | 0.76 | GRIN1 (0.40) | DRD2DRD4DRD3KCNH2HTR4 | |
| SCHEMBL6334076 | 0.75 | KCNH2 (0.43) | DRD2DRD4DRD3KCNH2HTR4 | |
| SCHEMBL6336361 | 0.75 | DRD2 (0.41) | DRD2DRD4DRD3HTR4 | |
| SCHEMBL6329269 | 0.74 | DRD2 (0.58) | DRD2DRD4DRD3HTR4 | |
| SCHEMBL6329579 | 0.72 | HTR4 (0.54) | HTR4 | |
| SCHEMBL6328985 | 0.72 | HTR4 (0.41) | DRD2DRD4DRD3KCNH2HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057688-A2 | OXO OR OXY-PYRIDINE COMPOUNDS AS 5-HT4 RECEPTOR MODULATORS | PFIZER JAPAN INC. (JP) | 2003-07-17 | — | — | WO | disclosed |