Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.43 |
| ▸ | CTSL | P07711 | 8/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063245 | 0.87 | CTSS (0.45) | CTSSCTSLCTSKFAAH | |
| SCHEMBL5946271 | 0.84 | CTSS (0.39) | CTSSCTSLCTSKFAAH | |
| Hydrochloric Acid SCHEMBL7255797 | 0.80 | CTSS (0.47) | CTSSCTSLCTSKALDH1A1L3MBTL1 | |
| SCHEMBL5945930 | 0.79 | CTSS (0.48) | CTSS | |
| SCHEMBL7255828 | 0.79 | CTSS (0.48) | CTSSCTSLCTSK | |
| SCHEMBL6206920 | 0.77 | CTSS (0.41) | CTSSFAAHALDH1A1L3MBTL1LMNA | |
| SCHEMBL6061967 | 0.74 | CTSS (0.46) | CTSSCTSLCTSK | |
| SCHEMBL7259493 | 0.71 | CTSS (0.45) | CTSSCTSLCTSK | |
| SCHEMBL5703798 | 0.71 | CTSS (0.44) | CTSSCTSLCTSK | |
| SCHEMBL6206025 | 0.70 | MAPT (0.39) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004000838-A1 | PEPTIDIC COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-31 | — | — | WO | disclosed |