Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827038 | 0.86 | ALDH1A1 (0.54) | NPSR1ALDH1A1TDP1KDM4ENPC1 | |
| SCHEMBL28139744 | 0.84 | FASN (0.48) | NPSR1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL26193086 | 0.83 | ALDH1A1 (0.51) | NPSR1ALDH1A1TDP1KDM4ENPC1 | |
| SCHEMBL25304674 | 0.83 | CYP11B2 (0.51) | NPSR1ALDH1A1KDM4EGABRG2GABRB3 | |
| SCHEMBL7213782 | 0.82 | NPSR1 (0.53) | NPSR1ALDH1A1TDP1KDM4ENPC1 | |
| SCHEMBL25302045 | 0.80 | AR (0.44) | ALDH1A1KDM4ECYP11B2CYP11B1 | |
| SCHEMBL4072388 | 0.79 | LDHA (0.53) | NPSR1ALDH1A1TDP1KDM4ENPC1 | |
| SCHEMBL16052482 | 0.78 | SMO (0.43) | — | |
| SCHEMBL7015435 | 0.77 | ALDH1A1 (0.46) | NPSR1ALDH1A1TDP1KDM4ENPC1 | |
| SCHEMBL7219026 | 0.77 | GABRG2 (0.50) | NPSR1ALDH1A1TDP1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080609-A1 | PYRAZOLOPYRIMIDINES DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-10-02 | — | — | WO | disclosed |