Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260700 | 0.87 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1LMNAPKM | |
| SCHEMBL599846 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1LMNAPKM | |
| SCHEMBL8760090 | 0.80 | UPP1 (0.49) | ALDH1A1TSHRMAPK1NPSR1CYP2C9 | |
| SCHEMBL9597854 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPK1LMNAPKM | |
| SCHEMBL7757667 | 0.77 | LMNA (0.52) | ALDH1A1TSHRLMNAPKMSMN1; SMN2 | |
| SCHEMBL7259761 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1LMNAPKM | |
| SCHEMBL7213295 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1LMNAPKM | |
| SCHEMBL7758853 | 0.75 | LMNA (0.38) | ALDH1A1TSHRMAPK1LMNAPKM | |
| SCHEMBL7756601 | 0.75 | ALDH1A1 (0.37) | ALDH1A1TSHRMAPK1LMNAPKM | |
| SCHEMBL7756583 | 0.74 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPK1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057677-A1 | ANTI-RETROVIRAL 5,6-DISUBSTITUTED ACYCLOPYRIMIDINE NUCLEOSIDE DERIVATIVES | SYDDANSK UNIVERSITET (DK) | 2003-07-17 | — | — | WO | disclosed |