Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TK1 | P04183 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259755 | 0.87 | ALDH1A1 (0.34) | ALDH1A1LMNAPKMTSHRMAPK1 | |
| SCHEMBL7213302 | 0.82 | MAPK1 (0.44) | ALDH1A1LMNAPKMTSHRMAPK1 | |
| Hept SCHEMBL384288 | 0.79 | UPP1 (0.48) | ALDH1A1TSHRMAPK1NPSR1HPGD | |
| SCHEMBL7015162 | 0.79 | ALDH1A1 (0.58) | ALDH1A1LMNAPKMTSHRMAPK1 | |
| SCHEMBL7219572 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPK1NPSR1HPGD | |
| SCHEMBL7255943 | 0.77 | ALDH1A1 (0.38) | ALDH1A1HPGDTK1L3MBTL1TLR7 | |
| SCHEMBL7219920 | 0.76 | ALDH1A1 (0.52) | ALDH1A1LMNAPKMTSHRMAPK1 | |
| SCHEMBL7260701 | 0.75 | LMNA (0.37) | ALDH1A1LMNAPKMTSHRMAPK1 | |
| SCHEMBL7215341 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNAPKMTSHRMAPK1 | |
| SCHEMBL8770174 | 0.74 | UPP1 (0.42) | ALDH1A1LMNAPKMTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057677-A1 | ANTI-RETROVIRAL 5,6-DISUBSTITUTED ACYCLOPYRIMIDINE NUCLEOSIDE DERIVATIVES | SYDDANSK UNIVERSITET (DK) | 2003-07-17 | — | — | WO | disclosed |