Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | RPA1 | P27694 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7758222 | 0.84 | SMN1; SMN2 (0.35) | ALDH1A1SMN1; SMN2PKMMEN1KMT2A | |
| SCHEMBL7213295 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2PKMTSHRMAPK1 | |
| SCHEMBL7757667 | 0.80 | LMNA (0.52) | ALDH1A1SMN1; SMN2PKMTSHRLMNA | |
| SCHEMBL599846 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2PKMTSHRMAPK1 | |
| SCHEMBL9009424 | 0.80 | DHFR (0.39) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL7756583 | 0.79 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2PKMTSHRMAPK1 | |
| SCHEMBL7756577 | 0.79 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2PKMTSHRMAPK1 | |
| SCHEMBL9597854 | 0.78 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2PKMTSHRMAPK1 | |
| SCHEMBL7758853 | 0.78 | LMNA (0.38) | ALDH1A1SMN1; SMN2PKMTSHRMAPK1 | |
| SCHEMBL7067258 | 0.77 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2PKMTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |
| US-5747500-A | VIRICIDES FOR AIDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-05-05 | — | — | US | disclosed |
| WO-1995018109-A1 | NOVEL ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-06 | — | — | WO | disclosed |