Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 13/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050206 | 0.93 | MMP1 (0.36) | MMP1MMP2MMP9MMP12CACNA1B | |
| SCHEMBL7263882 | 0.84 | MMP1 (0.47) | MMP1MMP2MMP9MMP12CACNA1B | |
| SCHEMBL8164747 | 0.81 | MMP1 (0.49) | MMP1MMP2MMP9MMP12CACNA1B | |
| SCHEMBL7263120 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TSHRHSD17B10CYP3A4 | |
| SCHEMBL5048998 | 0.76 | RAB9A (0.38) | ALDH1A1CYP3A4 | |
| SCHEMBL5050337 | 0.76 | MMP1 (0.38) | MMP1MMP2MMP9MMP12CACNA1B | |
| Cinnamyl Anthranilate SCHEMBL826957 | 0.75 | ALDH1A1 (0.63) | MMP1MMP2MMP9MMP12CACNA1B | |
| Cinnamyl Anthranilate SCHEMBL14764170 | 0.75 | ALDH1A1 (0.63) | MMP1MMP2MMP9MMP12CACNA1B | |
| Cinnamyl Anthranilate SCHEMBL826956 | 0.75 | ALDH1A1 (0.63) | MMP1MMP2MMP9MMP12CACNA1B | |
| SCHEMBL8159837 | 0.74 | MMP1 (0.52) | MMP1MMP2MMP9MMP12CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370298-A1 | ELONGATED AND MULTIPLE SPACERS IN ACTIVATIBLE PRODRUGS | Syntarga B.V. (NL) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002083180-A1 | ELONGATED AND MULTIPLE SPACERS IN ACTIVATIBLE PRODRUGS | SYNTARGA B.V. (NL) | 2002-10-24 | — | — | WO | disclosed |