Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048998 | 0.82 | RAB9A (0.38) | ALDH1A1RAB9ANPC1L3MBTL1CYP3A4 | |
| SCHEMBL7260048 | 0.77 | MMP1 (0.44) | ALDH1A1HSD17B10TSHRCYP3A4 | |
| SCHEMBL5050206 | 0.74 | MMP1 (0.36) | ALDH1A1HSD17B10TSHRCYP3A4 | |
| SCHEMBL28917944 | 0.68 | EGFR (0.40) | ALDH1A1RAB9ATDP1 | |
| SCHEMBL4445832 | 0.68 | PPARG (0.61) | ALDH1A1TSHRRAB9AKDM4ENPC1 | |
| SCHEMBL1560611 | 0.67 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TSHRRAB9AKDM4E | |
| SCHEMBL11462044 | 0.66 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TSHRRAB9AKDM4E | |
| SCHEMBL446689 | 0.66 | SMN1; SMN2 (0.43) | ALDH1A1HSD17B10TSHRRAB9AKDM4E | |
| SCHEMBL31253931 | 0.66 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TSHRRAB9AKDM4E | |
| SCHEMBL31253930 | 0.66 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TSHRRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370298-A1 | ELONGATED AND MULTIPLE SPACERS IN ACTIVATIBLE PRODRUGS | Syntarga B.V. (NL) | 2003-12-17 | — | — | EP | claimed |
| WO-2002083180-A1 | ELONGATED AND MULTIPLE SPACERS IN ACTIVATIBLE PRODRUGS | SYNTARGA B.V. (NL) | 2002-10-24 | — | — | WO | claimed |