Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 9/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.35 |
| ▸ | EGFR | P00533 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260141 | 0.80 | RAB9A (0.39) | RAB9APOLBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7260150 | 0.80 | RAB9A (0.39) | RAB9APOLBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7260154 | 0.79 | RAB9A (0.35) | RAB9APOLBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7105520 | 0.78 | F7 (0.36) | RAB9APOLBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7105193 | 0.77 | RAB9A (0.42) | RAB9APOLBMAPTSMN1; SMN2ERBB2 | |
| SCHEMBL7714235 | 0.72 | MAPT (0.36) | POLBMAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL7716176 | 0.71 | AKR1C3 (0.36) | MAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL7716173 | 0.67 | MAPT (0.37) | POLBMAPTSMN1; SMN2NPC1KMT2A | |
| SCHEMBL7105190 | 0.65 | RAB9A (0.47) | RAB9APOLBMAPTSMN1; SMN2ERBB2 | |
| SCHEMBL6888636 | 0.65 | RAB9A (0.47) | RAB9APOLBMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518283-B1 | To modify integrin function in such a way as to beneficially modulate cell adhesion | CELLTECH R&D LIMITED (GB) | 2003-02-11 | — | — | US | disclosed |