Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 3/20 | 0.60 |
| ▸ | GSK3B | P49841 | 3/20 | 0.60 |
| ▸ | CMA1 | P23946 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1770584 | 0.86 | GSK3A (0.55) | GSK3AGSK3BCMA1GAAGRM2 | |
| SCHEMBL22421493 | 0.81 | MGLL (0.56) | GSK3AGSK3BALDH1A1MEN1KMT2A | |
| SCHEMBL2660934 | 0.79 | MAOB (0.48) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL23997345 | 0.77 | FAAH (0.41) | GRM2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL17360667 | 0.77 | CMA1 (0.59) | GSK3AGSK3BCMA1GAAGRM2 | |
| SCHEMBL30783424 | 0.77 | SIGMAR1 (0.48) | GSK3AGSK3BCMA1GAAALDH1A1 | |
| SCHEMBL30293250 | 0.77 | GSK3A (0.42) | GSK3AGSK3BCMA1GAAGRM2 | |
| SCHEMBL28875188 | 0.77 | APLNR (0.50) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10641903 | 0.77 | GSK3A (0.53) | GSK3AGSK3BCMA1ALDH1A1MAPT | |
| SCHEMBL3384174 | 0.75 | GSK3A (1.00) | GSK3AGSK3BCMA1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099801-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-04 | — | — | WO | disclosed |