Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 10/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260372 | 0.87 | MAPK14 (0.45) | CYP2C9MAPK14 | |
| SCHEMBL7260381 | 0.81 | NPC1 (0.46) | KMT2AHPGDSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL7265103 | 0.81 | NPC1 (0.46) | KMT2AHPGDSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL7266685 | 0.81 | NPSR1 (0.49) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL7261724 | 0.80 | CD274 (0.56) | HPGDSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL7266288 | 0.80 | NPC1 (0.47) | KMT2AHPGDSMN1; SMN2RAB9ALMNA | |
| SCHEMBL7260411 | 0.79 | PARP1 (0.41) | — | |
| SCHEMBL7266274 | 0.79 | HPGD (0.48) | KMT2AMEN1HPGDL3MBTL1ATM | |
| SCHEMBL7261085 | 0.78 | MMP13 (0.49) | SMN1; SMN2RAB9ALMNAALDH1A1NPC1 | |
| SCHEMBL7266750 | 0.76 | NAMPT (0.44) | LMNATP53CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103666-A2 | NOVEL 4,5-DIHYDRO-IMIDAZO[4,5,1-IJ]QUINOLIN-6-ONES | ALTANA PHARMA AG (DE) | 2003-12-18 | — | — | WO | claimed |
| WO-2003103666-A2 | NOVEL 4,5-DIHYDRO-IMIDAZO[4,5,1-IJ]QUINOLIN-6-ONES | ALTANA PHARMA AG (DE) | 2003-12-18 | — | — | WO | disclosed |