Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PYGM | P11217 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261085 | 0.83 | MMP13 (0.49) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7265019 | 0.82 | LMNA (0.52) | HPGDKDM4EALDH1A1POLBHSD17B10 | |
| SCHEMBL7260372 | 0.81 | MAPK14 (0.45) | — | |
| SCHEMBL7266288 | 0.81 | NPC1 (0.47) | HPGDKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7261120 | 0.81 | ALDH1A1 (0.48) | TDP1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL7266750 | 0.81 | NAMPT (0.44) | LMNA | |
| SCHEMBL7266685 | 0.80 | NPSR1 (0.49) | HPGDCYP1A2KDM4EALDH1A1KMT2A | |
| SCHEMBL7261724 | 0.80 | CD274 (0.56) | HPGDCYP1A2ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7266279 | 0.77 | PARP1 (0.42) | HPGDCYP1A2ALDH1A1MAPTTSHR | |
| SCHEMBL7260381 | 0.77 | NPC1 (0.46) | HPGDCYP1A2ALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103666-A2 | NOVEL 4,5-DIHYDRO-IMIDAZO[4,5,1-IJ]QUINOLIN-6-ONES | ALTANA PHARMA AG (DE) | 2003-12-18 | — | — | WO | claimed |
| WO-2003103666-A2 | NOVEL 4,5-DIHYDRO-IMIDAZO[4,5,1-IJ]QUINOLIN-6-ONES | ALTANA PHARMA AG (DE) | 2003-12-18 | — | — | WO | disclosed |