Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5916381 | 0.84 | LMNA (0.44) | CYP2C9HSD17B10POLBTDP1ALDH1A1 | |
| SCHEMBL8007725 | 0.81 | CPN1 (0.47) | CYP2C9HSD17B10POLBSMN1; SMN2TDP1 | |
| SCHEMBL16738660 | 0.81 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL16633436 | 0.78 | HRH3 (0.43) | POLBALDH1A1 | |
| SCHEMBL9052921 | 0.75 | CYP2C9 (0.55) | CYP2C9HSD17B10MEN1KMT2A | |
| SCHEMBL28429862 | 0.74 | ESR1 (0.40) | HSD17B10TDP1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL19276561 | 0.72 | TDP1 (0.40) | CYP2C9HSD17B10TDP1ALDH1A1KDM4E | |
| SCHEMBL7067944 | 0.72 | TUBB4A (0.46) | CYP2C9HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL3096724 | 0.72 | ALDH1A1 (0.46) | CYP2C9HSD17B10SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL4246611 | 0.69 | CYP1A2 (0.44) | CYP2C9ALDH1A1KDM4ECYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534513-B1 | Antiinflammatory agents and fibronectins | CELLTECH R&D LIMITED (GB) | 2003-03-18 | — | — | US | disclosed |