SCHEMBL8007725

SCHEMBL8007725

CCC(c1cccc(N)c1)C(CC)(C(=O)O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 1/20 0.47
CPB2 Q96IY4 1/20 0.47
PBRM1 Q86U86 1/20 0.39
CYP2C9 P11712 2/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 1/20 0.38
ADRB2 P07550 2/20 0.37
ADRB1 P08588 2/20 0.37
ADRB3 P13945 2/20 0.37
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 3/20 0.36
GRM2 Q14416 1/20 0.36
GRM3 Q14832 1/20 0.36
POLB P06746 2/20 0.35
HPGDS O60760 1/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5916381 0.82 LMNA (0.44) CYP2C9HSD17B10ALDH1A1KDM4ETDP1
SCHEMBL3096724 0.82 ALDH1A1 (0.46) CYP2C9HSD17B10ALDH1A1MEN1KMT2A
SCHEMBL7260554 0.81 CYP2C9 (0.39) CYP2C9HSD17B10ALDH1A1KDM4ETDP1
SCHEMBL1205554 0.78 TP53 (0.47) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL9052921 0.77 CYP2C9 (0.55) CYP2C9HSD17B10MEN1KMT2A
SCHEMBL750097 0.73 CPN1 (0.71) CPN1CPB2PBRM1HSD17B10ALDH1A1
SCHEMBL16738660 0.73 ALDH1A1 (0.48) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL9402905 0.71 CPN1 (0.49) CPN1CPB2ALDH1A1TDP1LMNA
SCHEMBL9210125 0.71 CPN1 (0.50) CPN1CPB2PBRM1CYP2C9TDP1
SCHEMBL7067944 0.70 TUBB4A (0.46) CYP2C9HSD17B10ALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6099625-A Ink composition ZENECA LIMITED (GB) 2000-08-08 US disclosed
EP-0823927-A2 INK COMPOSITION ZENECA LIMITED (GB) 1998-02-18 EP disclosed
WO-1996034916-A2 INK COMPOSITION ZENECA LIMITED (GB) 1996-11-07 WO disclosed