Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | TK1 | P04183 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259761 | 0.87 | ALDH1A1 (0.36) | LMNANPSR1PKMTSHRMAPK1 | |
| SCHEMBL7213302 | 0.82 | MAPK1 (0.44) | LMNANPSR1PKMTSHRMAPK1 | |
| SCHEMBL7015162 | 0.79 | ALDH1A1 (0.58) | LMNANPSR1PKMTSHRMAPK1 | |
| SCHEMBL7255945 | 0.77 | ALDH1A1 (0.38) | LMNANPSR1TSHRMAPK1ALDH1A1 | |
| Hept SCHEMBL384288 | 0.77 | UPP1 (0.48) | NPSR1TSHRMAPK1ALDH1A1HPGD | |
| SCHEMBL7219920 | 0.76 | ALDH1A1 (0.52) | LMNANPSR1PKMTSHRMAPK1 | |
| SCHEMBL7260700 | 0.75 | ALDH1A1 (0.36) | LMNANPSR1PKMTSHRMAPK1 | |
| SCHEMBL7219572 | 0.73 | ALDH1A1 (0.39) | NPSR1TSHRMAPK1ALDH1A1HPGD | |
| SCHEMBL7215330 | 0.73 | ALDH1A1 (0.43) | LMNANPSR1PKMTSHRMAPK1 | |
| SCHEMBL9357368 | 0.72 | ALDH1A1 (0.35) | LMNANPSR1PKMTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057677-A1 | ANTI-RETROVIRAL 5,6-DISUBSTITUTED ACYCLOPYRIMIDINE NUCLEOSIDE DERIVATIVES | SYDDANSK UNIVERSITET (DK) | 2003-07-17 | — | — | WO | disclosed |