Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254926 | 0.88 | MEN1 (0.36) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7031964 | 0.87 | KMT2A (0.39) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7254987 | 0.86 | ALDH1A1 (0.37) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7758274 | 0.85 | TPH1 (0.37) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7255132 | 0.84 | MEN1 (0.36) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7259855 | 0.82 | MEN1 (0.36) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7254871 | 0.81 | ALDH1A1 (0.32) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8073601 | 0.81 | ALDH1A1 (0.51) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6087754 | 0.81 | KMT2A (0.39) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12752168 | 0.80 | KMT2A (0.40) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057677-A1 | ANTI-RETROVIRAL 5,6-DISUBSTITUTED ACYCLOPYRIMIDINE NUCLEOSIDE DERIVATIVES | SYDDANSK UNIVERSITET (DK) | 2003-07-17 | — | — | WO | disclosed |