SCHEMBL7260907

SCHEMBL7260907

C/C(=N\c1ccccc1)N(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 7/20 0.56
NOS3 P29474 4/20 0.56
HTR3E A5X5Y0 2/20 0.46
HTR3B O95264 2/20 0.46
HTR3A P46098 2/20 0.46
HTR3D Q70Z44 2/20 0.46
HTR3C Q8WXA8 2/20 0.46
SLC22A2 O15244 1/20 0.46
SLC22A1 O15245 1/20 0.46
SLC22A3 O75751 1/20 0.46
PLAU P00749 1/20 0.46
MAPT P10636 3/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 4/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7260909 1.00 NOS1 (0.56) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL24201199 0.80 NOS1 (0.50) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL3067533 0.80 NOS1 (0.50) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL3067531 0.80 NOS1 (0.50) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL15159798 0.79 HTR3E (0.52) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL15153262 0.79 HTR3E (0.52) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL3935554 0.78 NOS1 (0.39) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL3935558 0.78 NOS1 (0.39) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL13962398 0.78 NOS1 (0.39) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL664694 0.78 NOS1 (0.52) NOS1NOS3HTR3EHTR3BHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0684620-B1 ELECTROLYTIC SOLUTION AND ELECTROCHEMICAL ELEMENT PREPARED THEREFROM SANYO CHEMICAL IND LTD (JP) 2003-06-04 EP disclosed
US-5870275-A CONTAINING A QUATERNARY AMIDINE GROUP SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1999-02-09 US disclosed
EP-0684620-A1 ELECTROLYTIC SOLUTION AND ELECTROCHEMICAL ELEMENT PREPARED THEREFROM SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1995-11-29 EP disclosed
US-4448975-A Process for the preparation of substituted amidines GENERAL ELECTRIC COMPANY (US) 1984-05-15 US disclosed
US-4353830-A Process for the preparation of substituted amidines GENERAL ELECTRIC COMPANY (US) 1982-10-12 US disclosed
US-4321202-A 1-Methyl-2(alkylimino)pyrrolidines and 1-methyl 2(cycloalkylimino) pyrrolidines GENERAL ELECTRIC COMPANY (US) 1982-03-23 US disclosed
US-4262111-A INTERFACIAL POLYMERIZATION PRODUCING HIGH MOLECULAR WEIGHT POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 1981-04-14 US disclosed
US-4064270-A ANTHELMINTICS BAYER AKTIENGESELLSCHAFT (DT) 1977-12-20 US disclosed
US-4015012-A ANTHELMINTICS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed
US-3970699-A 4-Acylaminophenylacetamidines and a method for their preparation BAYER AKTIENGESELLSCHAFT (DT) 1976-07-20 US disclosed