Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.52 |
| ▸ | NOS3 | P29474 | 4/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.48 |
| ▸ | HTR3B | O95264 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL2229425 | 0.89 | NOS1 (0.54) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL5935352 | 0.87 | ADRA2A (0.44) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL10072502 | 0.87 | NOS1 (0.45) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL13381445 | 0.87 | NOS1 (0.50) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL5746645 | 0.83 | NOS1 (0.54) | NOS1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7260909 | 0.78 | NOS1 (0.56) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL7260907 | 0.78 | NOS1 (0.56) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL10533424 | 0.78 | HTR3E (0.54) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL5745399 | 0.77 | SIGMAR1 (0.37) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL3066162 | 0.76 | HTR3E (0.56) | NOS1NOS3HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104177362-B | A kind of adjustable ionic liquid of polarity and the preparation method and application thereof | 中国石油大学(北京) | 2019-03-08 | — | — | CN | claimed |
| CN-104177362-A | Polarity-adjustable ionic liquid, and preparation method and application thereof | UNIV CHINA PETROLEUM | 2014-12-03 | — | — | CN | claimed |
| US-8846851-B2 | Methods of ring opening polymerization and catalysts therefor | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-09-30 | — | — | US | claimed |
| US-8491790-B2 | Method for the direct elution of reactive 18F fluoride from an anion exchange resin in an organic medium suitable for radiolabelling without any evaporation step by the use of strong organic bases | TRASIS S.A. (BE) | 2013-07-23 | — | — | US | claimed |
| US-20130158226-A1 | METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-06-20 | — | — | US | claimed |
| EP-2164590-B1 | METHOD FOR THE DIRECT ELUTION OF REACTIVE 18F FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF STRONG ORGANIC BASES | TRASIS S A (BE) | 2013-03-06 | — | — | EP | claimed |
| US-20120046437-A1 | METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-02-23 | — | — | US | claimed |
| US-20100196254-A1 | METHOD FOR THE DIRECT ELUTION OF REACTIVE 18F FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF STRONG ORGANIC BASES | TRASIS S.A. (BE) | 2010-08-05 | — | — | US | claimed |
| EP-4225822-B1 | METHOD FOR PRODUCING POLYURETHANE FOAMS OR HYDROGELS BY EMPLOYING DIOL CONTAINING FORMULATIONS | COVESTRO DEUTSCHLAND AG (DE) | 2026-05-13 | — | — | EP | disclosed |
| EP-4569023-A1 | COMBINATION OF CATALYTIC COMPONENTS | PolyU GmbH (DE) | 2025-06-18 | — | — | EP | disclosed |
| US-20240368443-A1 | METHOD FOR PREPARING A POLYURETHANE POLYMER | BOSTIK SA (FR) | 2024-11-07 | — | — | US | disclosed |
| EP-3582816-B1 | METHOD FOR PRODUCING AN ADHESIVE-FREE WOUND CONTACT MATERIAL | COVESTRO DEUTSCHLAND AG (DE) | 2024-10-30 | — | — | EP | disclosed |
| EP-3737429-B1 | METHOD FOR THE MANUFACTURE OF ELASTIC AND TEAR-RESISTANT POLYURETHANE FOAMS AND THEIR APPLICATIONS | COVESTRO DEUTSCHLAND AG (DE) | 2024-03-20 | — | — | EP | disclosed |
| WO-2024033348-A1 | COMBINATION OF CATALYTIC COMPONENTS | POLYU GMBH (DE) | 2024-02-15 | — | — | WO | disclosed |
| EP-0600546-A1 | Binder composition for powder paints | DSM N.V. (NL) | 1994-06-08 | — | — | EP | disclosed |
| US-5082968-A | Alkylation, salt formation | GENERAL ELECTRIC COMPANY (US) | 1992-01-21 | — | — | US | disclosed |
| US-4358613-A | Process for the preparation of substituted guanidines | GENERAL ELECTRIC COMPANY (US) | 1982-11-09 | — | — | US | disclosed |
| US-4191815-A | DIAZABICYCLOALKENE, GUANIDINE, AND BIGUANIDINE CATALYSTS | S.A. PRB (BE) | 1980-03-04 | — | — | US | disclosed |
| US-4073636-A | Azolylamidine compounds and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DT) | 1978-02-14 | — | — | US | disclosed |
| US-3993469-A | Azolylamidine compounds and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046437-A1 | METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR | OGFOD1, PCNA, ODC1 | NOS1 62/4885NOS3 182/4885HTR3E 4740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.