SCHEMBL7261502

SCHEMBL7261502

COC(=O)CC1CN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.54
NAMPT P43490 1/20 0.48
BRD4 O60885 1/20 0.47
USP2 O75604 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
EPHX1 P07099 1/20 0.40
PDE4B Q07343 1/20 0.40
KDM4E B2RXH2 1/20 0.39
PKM P14618 1/20 0.39
GLS O94925 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
HPGD P15428 1/20 0.39
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19511364 0.88 KDM4E (0.47) NR1H2BRD4EPHX1KDM4EPKM
SCHEMBL852498 0.88 KDM4E (0.47) NR1H2BRD4EPHX1KDM4EPKM
SCHEMBL20565243 0.88 KDM4E (0.47) NR1H2BRD4EPHX1KDM4EPKM
SCHEMBL22270687 0.88 NR1H2 (0.68) NR1H2NAMPTBRD4USP2SMN1; SMN2
SCHEMBL22387486 0.88 NR1H2 (0.68) NR1H2NAMPTBRD4USP2SMN1; SMN2
SCHEMBL29030935 0.88 NR1H2 (0.68) NR1H2NAMPTBRD4USP2SMN1; SMN2
SCHEMBL1048155 0.85 GLS (0.54) NR1H2EPHX1GLSALDH1A1MEN1
SCHEMBL1048156 0.85 GLS (0.54) NR1H2EPHX1GLSALDH1A1MEN1
SCHEMBL30922668 0.85 GLS (0.54) NR1H2EPHX1GLSALDH1A1MEN1
SCHEMBL25145273 0.84 NR1H2 (0.48) NR1H2NAMPTBRD4USP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098560-A2 BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-15 WO disclosed
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
EP-4539840-A1 KINASE MODULATORS AND METHODS OF USE THEREOF Neuron23, Inc. (US) 2025-04-23 EP disclosed
US-20250114460-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND UPPTHERA, INC. (KR) 2025-04-10 US disclosed
EP-4463450-A1 FUSED HETEROARYL HYDROXAMATES AS STING AGONISTS Bisichem Co., Ltd. (KR) 2024-11-20 EP disclosed
EP-4463459-A1 STAT MODULATORS AND USES THEREOF Recludix Pharma, Inc. (US) 2024-11-20 EP disclosed
US-20240336596-A1 PARP7 INHIBITOR AND USE THEREOF NOVOSTAR PHARMACEUTICALS, LTD. (CN) 2024-10-10 US disclosed
WO-2023244788-A9 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2024-09-12 WO disclosed
EP-4384520-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND Uppthera, Inc. (KR) 2024-06-19 EP disclosed
CN-118076607-A Novel PLK1 degradation inducing compounds 厄普特拉株式会社 2024-05-24 CN disclosed
US-20130296293-A1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS MERCK SHARP & DOHME LLC 2013-11-07 US disclosed
US-20130296290-A1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS MERCK SHARP & DOHME LLC 2013-11-07 US disclosed
US-20130296290-A1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS MERCK SHARP & DOHME LLC 2013-11-07 US disclosed
US-20130296293-A1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS MERCK SHARP & DOHME LLC 2013-11-07 US disclosed
US-20130296292-A1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS MERCK SHARP & DOHME LLC 2013-11-07 US disclosed
US-20130296291-A1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS MERCK SHARP & DOHME LLC 2013-11-07 US disclosed
US-20130296291-A1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS MERCK SHARP & DOHME LLC 2013-11-07 US disclosed
WO-2013149121-A1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS CUBIST PHARMACEUTICALS, INC. (US) 2013-10-03 WO disclosed
WO-2013149136-A1 ISOXAZOLE β-LACTAMASE INHIBITORS CUBIST PHARMACEUTICALS, INC. (US) 2013-10-03 WO disclosed
WO-2003013526-A1 ANTICOAGULANT COMPOUNDS MERCK & CO. INC. (US) 2003-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130296293-A1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS BTD, BLVRB, PEPD NR1H2 3323/4885NAMPT 1133/4885BRD4 406/4885
US-20130296290-A1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS BTD, BLVRB, PEPD NR1H2 3323/4885NAMPT 1133/4885BRD4 406/4885
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A NR1H2 926/4885NAMPT 1463/4885BRD4 318/4885
US-20240336596-A1 PARP7 INHIBITOR AND USE THEREOF PARP1, PARP3, PARP11 NR1H2 3155/4885NAMPT 101/4885BRD4 205/4885
US-20130296291-A1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS BTD, BLVRB, PEPD NR1H2 3323/4885NAMPT 1133/4885BRD4 406/4885
US-20250114460-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND PLK1, BUB1B, BUB1 NR1H2 2448/4885NAMPT 2936/4885BRD4 903/4885
US-20130296292-A1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS BTD, BLVRB, PEPD NR1H2 3323/4885NAMPT 1133/4885BRD4 406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.