Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYCS | P99999 | 4/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29408468 | 0.90 | TERT (0.51) | TOP1ABCG2TERTMEN1ALDH1A1 | |
| SCHEMBL498495 | 0.90 | TERT (0.51) | TOP1ABCG2TERTMEN1ALDH1A1 | |
| SCHEMBL3424111 | 0.84 | TOP1 (0.81) | TOP1ABCG2TERTCYCSENPP2 | |
| SCHEMBL9391899 | 0.83 | TOP1 (0.70) | TOP1ABCG2TERTCYCSENPP2 | |
| SCHEMBL949511 | 0.82 | TERT (0.57) | TOP1ABCG2TERTNPC1ALDH1A1 | |
| SCHEMBL29414382 | 0.82 | TERT (0.57) | TOP1ABCG2TERTNPC1ALDH1A1 | |
| SCHEMBL16438041 | 0.82 | TOP1 (0.79) | TOP1ABCG2TERTCYCSENPP2 | |
| SCHEMBL31337529 | 0.82 | TOP1 (0.79) | TOP1ABCG2TERTCYCSENPP2 | |
| SCHEMBL3802533 | 0.82 | TOP1 (0.79) | TOP1ABCG2TERTCYCSENPP2 | |
| Hydrochloric Acid SCHEMBL8908213 | 0.82 | TOP1 (0.79) | TOP1ABCG2TERTCYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203888-A1 | Chromophores | WELLCOME TRUST LIMITED, THE (GB) | 2003-10-30 | — | — | US | disclosed |
| EP-1294726-A2 | IMPROVEMENTS IN AND RELATING TO CHROMOPHORES | Catalyst Biomedica Ltd (GB) | 2003-03-26 | — | — | EP | disclosed |
| US-6419897-B1 | PORPHYRIN COMPOUNDS | ARIZONA BOARD OF REGENTS | 2002-07-16 | — | — | US | disclosed |
| WO-2002000662-A1 | IMPROVEMENTS IN AND RELATING TO CHROMOPHORES | CATALYST BIOMEDICA LIMITED (GB) | 2002-01-03 | — | — | WO | disclosed |
| US-6274729-B1 | PREVENT TISSUE DAMAGE | ARIZONA BOARD OF REGENTS | 2001-08-14 | — | — | US | disclosed |
| US-6183727-B1 | DETECTING A PATHOLOGY OR TARGET TISSUE BY ADMINISTERING A ZINC PHTHALOCYANINE DYES IMAGING MATERIAL AND EXPOSING TO RADIATION WITHOUT DAMAGING THE MAMMALIAN HOST | ARIZONA BOARD OF REGENTS | 2001-02-06 | — | — | US | disclosed |
| WO-1999059641-A1 | USE OF LONG-WAVELENGTH ELECTROMAGNETIC RADIATION OF DIAGNOSIS | ARIZONA BOARD OF REGENTS (US) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203888-A1 | Chromophores | HCCS, PPOX, HMBS | TOP1 1754/4885ABCG2 3547/4885TERT 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.