⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430424 | 0.68 | NPC1 (0.41) | — | |
| SCHEMBL11472840 | 0.67 | — | — | |
| SCHEMBL7486358 | 0.61 | — | — | |
| SCHEMBL11480120 | 0.61 | KMT2A (0.46) | — | |
| SCHEMBL10985990 | 0.60 | CDK5 (0.36) | — | |
| SCHEMBL8548510 | 0.60 | GOT1 (0.55) | — | |
| SCHEMBL17028924 | 0.60 | — | — | |
| SCHEMBL2086729 | 0.60 | — | — | |
| SCHEMBL3988243 | 0.60 | — | — | |
| SCHEMBL742184 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596706-B1 | For the treatment of circulatory diseases cerebral diseases | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | claimed |
| EP-0367484-B1 | Carboxylic acid derivates | GLAXO GROUP LTD (GB) | 1994-02-16 | — | — | EP | claimed |
| US-5273984-A | Bismuth complex having a carboxylic acid to form a salt of the basic antagonist excluding ranitidine | GLAXO GROUP LIMITED (GB) | 1993-12-28 | — | — | US | claimed |
| EP-0275669-B1 | USE OF HETEROCYCLIC DERIVATIVES FOR THE MANUFACTURE OF MEDICAMENTS | GLAXO GROUP LIMITED (GB) | 1992-09-30 | — | — | EP | claimed |
| EP-0454449-A1 | Carboxylic acid derivatives | GLAXO GROUP LIMITED (GB) | 1991-10-30 | — | — | EP | claimed |
| EP-0367484-A1 | Carboxylic acid derivates | GLAXO GROUP LIMITED (GB) | 1990-05-09 | — | — | EP | claimed |
| EP-0275669-A1 | Use of heterocyclic derivatives for the manufacture of medicaments | GLAXO GROUP LIMITED (GB) | 1988-07-27 | — | — | EP | claimed |
| EP-0367484-B1 | Carboxylic acid derivates | GLAXO GROUP LTD (GB) | 1994-02-16 | — | — | EP | disclosed |
| US-5273984-A | Bismuth complex having a carboxylic acid to form a salt of the basic antagonist excluding ranitidine | GLAXO GROUP LIMITED (GB) | 1993-12-28 | — | — | US | disclosed |
| US-5221688-A | Gastrointestinal disorders | GLAXO GROUP LIMITED (GB) | 1993-06-22 | — | — | US | disclosed |
| EP-0275669-B1 | USE OF HETEROCYCLIC DERIVATIVES FOR THE MANUFACTURE OF MEDICAMENTS | GLAXO GROUP LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |
| EP-0454449-A1 | Carboxylic acid derivatives | GLAXO GROUP LIMITED (GB) | 1991-10-30 | — | — | EP | disclosed |
| EP-0367484-A1 | Carboxylic acid derivates | GLAXO GROUP LIMITED (GB) | 1990-05-09 | — | — | EP | disclosed |
| EP-0275669-A1 | Use of heterocyclic derivatives for the manufacture of medicaments | GLAXO GROUP LIMITED (GB) | 1988-07-27 | — | — | EP | disclosed |
| EP-0073971-B1 | THIADIAZOLE OXIDES AS GASTRIC ANTISECRETORY AGENTS | MERCK & CO. INC. (US) | 1986-05-21 | — | — | EP | disclosed |
| US-4521418-A | HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-06-04 | — | — | US | disclosed |
| US-4521418-A | HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-06-04 | — | — | US | disclosed |
| EP-0074229-A1 | Triazole gastric anti-secretory agents | PFIZER INC. (US) | 1983-03-16 | — | — | EP | disclosed |