Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | PDE5A | O76074 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262122 | 0.83 | MAPT (0.41) | MAPTPDE5AKMT2APOLBMEN1 | |
| SCHEMBL9921503 | 0.78 | PDE5A (0.69) | MAPTPDE5ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1747920 | 0.77 | MAOA (0.54) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7420304 | 0.76 | PDE5A (0.68) | MAPTPDE5ASMN1; SMN2KMT2APOLB | |
| SCHEMBL8827458 | 0.74 | KMT2A (0.44) | MAPTPDE5ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1040562 | 0.74 | MAPT (0.76) | MAPTPDE5ASMN1; SMN2KMT2APOLB | |
| SCHEMBL8827465 | 0.73 | SMN1; SMN2 (0.44) | MAPTSMN1; SMN2KMT2APOLBMEN1 | |
| SCHEMBL20445842 | 0.73 | IDO1 (0.50) | MAPTPDE5AKMT2APOLBMEN1 | |
| SCHEMBL8827512 | 0.72 | MAPT (0.45) | MAPTPDE5ASMN1; SMN2KMT2APOLB | |
| SCHEMBL7010631 | 0.72 | MAPT (0.85) | MAPTPDE5ASMN1; SMN2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027057-A4 | TREATMENT OF FEMALE SEXUAL DYSFUNCTION | VIVUS INC (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-1027057-A1 | TREATMENT OF FEMALE SEXUAL DYSFUNCTION | Asivi, LLC (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999021562-A1 | TREATMENT OF FEMALE SEXUAL DYSFUNCTION | ASIVI, LLC (US) | 1999-05-06 | — | — | WO | disclosed |