Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262125 | 0.83 | MAPT (0.61) | MAPTKMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL8620057 | 0.73 | PDE5A (0.71) | MAPTKMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL8827458 | 0.73 | KMT2A (0.44) | MAPTKMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL5598718 | 0.71 | PDE4A (0.57) | PDE5ATDP1PIN1 | |
| SCHEMBL20445842 | 0.71 | IDO1 (0.50) | MAPTKMT2AMEN1PDE5APOLB | |
| SCHEMBL8827512 | 0.71 | MAPT (0.45) | MAPTKMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL8827465 | 0.70 | SMN1; SMN2 (0.44) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL27456953 | 0.67 | CYP1A2 (0.42) | MAPTKMT2APOLBALDH1A1GAA | |
| SCHEMBL5743821 | 0.66 | GSK3B (0.56) | MAPTKMT2AMEN1ACHEPOLB | |
| SCHEMBL27920418 | 0.65 | ALDH1A1 (0.46) | MAPTPOLBALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027057-A4 | TREATMENT OF FEMALE SEXUAL DYSFUNCTION | VIVUS INC (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-1027057-A1 | TREATMENT OF FEMALE SEXUAL DYSFUNCTION | Asivi, LLC (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999021562-A1 | TREATMENT OF FEMALE SEXUAL DYSFUNCTION | ASIVI, LLC (US) | 1999-05-06 | — | — | WO | disclosed |