Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 13/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262190 | 0.87 | KMT2A (0.47) | TACR1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL657234 | 0.83 | TDP1 (0.55) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL6915903 | 0.80 | MRGPRX4 (0.43) | NPC1RAB9AKMT2AMEN1HPGD | |
| SCHEMBL7928075 | 0.78 | KMT2A (0.53) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL1872900 | 0.77 | TACR1 (0.52) | TACR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3599787 | 0.77 | NPC1 (0.58) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| Chloroform SCHEMBL28141196 | 0.77 | NPC1 (0.49) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL10204480 | 0.77 | KMT2A (0.68) | TACR1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL864716 | 0.76 | MAPT (0.61) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL4689393 | 0.76 | RAB9A (0.56) | NPC1RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6657052-B1 | Labeling DNA or RNA at a specific site consisting of stable precursor, and only becomes reactive upon activation; alkylating only phosphodiester groups; lactonization reaction traps the trialkylphosphate in a stable form. | UNIVERSITY OF ARKANSAS | 2003-12-02 | — | — | US | disclosed |