Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262188 | 0.87 | TACR1 (0.50) | KMT2ANPC1RAB9AMEN1TACR1 | |
| SCHEMBL657234 | 0.83 | TDP1 (0.55) | KMT2AKDM4ENPC1RAB9ATSHR | |
| SCHEMBL6915906 | 0.80 | GLRA1 (0.44) | KMT2ANPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL12691361 | 0.78 | LMNA (0.56) | KMT2AKDM4EPOLBNPC1MEN1 | |
| SCHEMBL8864405 | 0.77 | PTPRC (0.59) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL8557631 | 0.77 | MEN1 (0.56) | KMT2ARAB9AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL2786958 | 0.77 | NPC1 (0.55) | NPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL12020911 | 0.77 | TDP1 (0.68) | KMT2AKDM4EPOLBNPC1RAB9A | |
| Chloroform SCHEMBL28141196 | 0.77 | NPC1 (0.49) | KMT2AKDM4ENPC1RAB9ATSHR | |
| SCHEMBL9653413 | 0.76 | NPC1 (0.65) | KMT2APOLBNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6657052-B1 | Labeling DNA or RNA at a specific site consisting of stable precursor, and only becomes reactive upon activation; alkylating only phosphodiester groups; lactonization reaction traps the trialkylphosphate in a stable form. | UNIVERSITY OF ARKANSAS | 2003-12-02 | — | — | US | disclosed |