SCHEMBL726307

SCHEMBL726307

S=P(Cl)(Cl)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
HTT P42858 2/20 0.41
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
NPSR1 Q6W5P4 8/20 0.35
TSHR P16473 1/20 0.35
CFTR P13569 1/20 0.35
LMNA P02545 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
ALPG P10696 1/20 0.33
ALOX12 P18054 1/20 0.33
NPY1R P25929 1/20 0.33
NPY2R P49146 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2502559 0.81 ESR1 (0.46) ESR1ESR2HTTCA2CA4
SCHEMBL11145389 0.77 ESR1 (0.42) ESR1ESR2HTTCA2CA4
SCHEMBL21557205 0.77 ESR1 (0.42) ESR1ESR2HTTCA2CA4
SCHEMBL8994040 0.77 ESR1 (0.48) ESR1ESR2HTTCA2CA4
SCHEMBL517954 0.76 ESR1 (0.68) ESR1ESR2HTTCA2CA4
SCHEMBL9772833 0.73 ESR1 (0.65) ESR1ESR2HTTCA2CA4
SCHEMBL10295074 0.73 ESR1 (0.50) ESR1ESR2HTTCA2CA4
Phosphine SCHEMBL15190577 0.73 ESR1 (0.65) ESR1ESR2HTTCA2CA4
SCHEMBL31176947 0.73 ESR1 (0.65) ESR1ESR2HTTCA2CA4
SCHEMBL99519 0.73 CA2 (0.43) ESR1ESR2HTTCA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595433-B2 Organic phosphorus compound, preparation method therefor, and uses thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2026-04-07 US claimed
CN-120025673-A Halogen-free flame-retardant composite plastic and preparation method thereof 江西绿聚科技有限公司 2025-05-23 CN claimed
CN-119371831-B Flame-retardant silica gel cable material and preparation method thereof 齐耐润科技(上海)股份有限公司 2025-05-09 CN claimed
US-20250034476-A1 ORGANIC PHOSPHORUS COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2025-01-30 US claimed
CN-119371831-A Flame-retardant silica gel cable material and preparation method thereof 齐耐润科技(上海)股份有限公司 2025-01-28 CN claimed
CN-119264182-A Compound, preparation method thereof, resin material and application thereof 珠海莫界科技有限公司 2025-01-07 CN claimed
CN-118571525-B TOPCon battery back nickel-copper slurry and preparation method thereof 江苏日御光伏新材料股份有限公司 2024-12-06 CN claimed
CN-118571525-A TOPCon battery back nickel-copper slurry and preparation method thereof 江苏日御光伏新材料股份有限公司 2024-08-30 CN claimed
CN-108091439-B Flame-retardant fire-resistant solar photovoltaic cable 扬州曙光电缆股份有限公司 2024-03-22 CN claimed
CN-108154960-B Flame-retardant fire-resistant anti-interference marine intrinsic safety instrument cable 扬州曙光电缆股份有限公司 2024-01-23 CN claimed
CN-1224635-C High refractive index thermoplastic polyphosphonates JOHNSON & JOHNSON VISION CARE (US) 2005-10-26 CN claimed
US-20050101755-A1 HIGH REFRACTIVE INDEX THERMOPLASTIC POLYPHOSPHONATES JOHNSON & JOHNSON VISION CARE, INC. 2005-05-12 US claimed
EP-1254190-A4 HIGH REFRACTIVE INDEX THERMOPLASTIC POLYPHOSPHONATES JOHNSON & JOHNSON VISION CARE (US) 2005-04-13 EP claimed
CN-1387545-A High refractive index thermoplastic polyphosphonates JOHNSON & JOHNSON VISION CARE (US) 2002-12-25 CN claimed
EP-1254190-A1 HIGH REFRACTIVE INDEX THERMOPLASTIC POLYPHOSPHONATES Johnson & Johnson Products, Inc. (US) 2002-11-06 EP claimed
US-20020058779-A1 High refractive index thermoplastic polyphosphonates JOHNSON & JOHNSON VISION PRODUCTS, INC., AND VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2002-05-16 US claimed
WO-2001034683-A1 HIGH REFRACTIVE INDEX THERMOPLASTIC POLYPHOSPHONATES JOHNSON & JOHNSON PRODUCTS, INC. (US) 2001-05-17 WO claimed
US-4816605-A Process for the preparation of bifunctional tertiary aromatic phosphine oxides HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-28 US claimed
EP-0214591-A2 Process for the preparation of bifunctional tertiary aromatic phosphanoxides HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-18 EP claimed
US-3988368-A ALUMINUM, ALUMINUM CHLORIDE, PHOSPHORUS SULFIDE, OR PHOSPHORUS CHLORIDE CATALYSTS; HYDROGEN CHLORIDE NISSAN CHEMICAL INDUSTRIES, LTD. (JA) 1976-10-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595433-B2 Organic phosphorus compound, preparation method therefor, and uses thereof NOTUM, GC, PHOSPHO1 ESR1 747/4885ESR2 927/4885HTT 4732/4885
US-20250034476-A1 ORGANIC PHOSPHORUS COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF SOST, NOTUM, WEE1 ESR1 1246/4885ESR2 2293/4885HTT 4637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.