SCHEMBL7263128

SCHEMBL7263128

C=CC(=O)Sc1cccc(Sc2cccc(SC(=O)C=C)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.37
HSD17B10 Q99714 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
SIRT1 Q96EB6 1/20 0.33
APEX1 P27695 1/20 0.33
ALDH1A1 P00352 2/20 0.32
AKT1 P31749 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
TERT O14746 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27460817 0.92 MAPT (0.40) HPGDHSD17B10CYP1A2CYP2C9ALDH1A1
SCHEMBL27460839 0.92 MAPT (0.40) HPGDHSD17B10CYP1A2CYP2C9ALDH1A1
SCHEMBL27460816 0.89 ALDH1A1 (0.37) HPGDHSD17B10CYP1A2CYP2C9ALDH1A1
SCHEMBL27460821 0.85 MCL1 (0.38) HPGDHSD17B10CYP1A2CYP2C9ALDH1A1
SCHEMBL27460818 0.83 POLB (0.39) HPGDHSD17B10SIRT1ALDH1A1MEN1
SCHEMBL15199707 0.81 TERT (0.49) HSD17B10HDAC8HDAC6TERTMEN1
SCHEMBL1023934 0.79 HPGD (0.41) HPGDCYP1A2CYP2C9APEX1ALDH1A1
SCHEMBL330818 0.79 AKT1 (0.46) HPGDHSD17B10CYP1A2CYP2C9ALDH1A1
SCHEMBL4857114 0.77 AKT1 (0.36) HPGDALDH1A1AKT1TGM2MAPT
SCHEMBL27460825 0.76 MEN1 (0.39) HPGDHSD17B10CYP1A2CYP2C9SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6558276-B1 Improved feeling without impairing intrinsic resilience; core made from rubber composition of a base rubber, an organic peroxide, an alpha, beta unsaturated carboxylic acid, and a bis type halogen-substituted phenyl disulfide SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2003-05-06 US disclosed
US-6241625-B1 A GOLF BALL COMPRISING A COVER MEMBER AND A CORE MEMBER, WHEREIN POLYAMIDE, TERPOLYMER IONOMER CONTAINING ETHYLENE, (METH)ACRYLIC ACID, AND (METH)ACRYLIC ESTER MIXTURES WITH PEROXIDE AND SULFIDE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2001-06-05 US disclosed