SCHEMBL330818

SCHEMBL330818

C=CC(=O)Sc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.46
TGM2 P21980 1/20 0.42
FFAR1 O14842 1/20 0.40
ALDH1A1 P00352 6/20 0.39
TSHR P16473 3/20 0.39
ALOX15 P16050 3/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
HPGD P15428 5/20 0.38
MAPT P10636 3/20 0.38
PLIN1 O60240 1/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
PLIN5 Q00G26 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ABHD5 Q8WTS1 1/20 0.38
HSD17B10 Q99714 3/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4857114 0.88 AKT1 (0.36) AKT1TGM2ALDH1A1TSHRHPGD
SCHEMBL4612199 0.88 AKT1 (0.41) AKT1TGM2ALDH1A1TSHRHPGD
SCHEMBL16170352 0.82 AKT1 (0.32) AKT1MAPT
SCHEMBL16170477 0.82 AKT1 (0.32) AKT1MAPT
SCHEMBL1023934 0.82 HPGD (0.41) AKT1ALDH1A1TSHRHPGDMAPT
SCHEMBL16170754 0.82 AKT1 (0.32) AKT1MAPT
Acrylic Acid SCHEMBL27803989 0.81 LMNA (0.40) AKT1TGM2ALDH1A1TSHRHPGD
SCHEMBL7263128 0.79 HPGD (0.37) AKT1TGM2ALDH1A1ALOX15HPGD
SCHEMBL16170601 0.79 HDAC8 (0.34) AKT1TGM2CYP1A2CYP2C9CYP2C19
SCHEMBL5158236 0.79 AKT1 (0.43) AKT1TGM2ALDH1A1TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260110823-A1 OPTICAL ELEMENT, OPTICAL APPARATUS, IMAGING APPARATUS, AND COMPOUND CANON KK (JP) 2026-04-23 US disclosed
US-12529822-B2 Optical element, optical apparatus, imaging apparatus, and compound CANON KABUSHIKI KAISHA (JP) 2026-01-20 US disclosed
CN-114437269-B Optical element, optical device, imaging device, and compound 佳能株式会社 2024-06-07 CN disclosed
EP-3345954-B1 POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE TOKUYAMA CORP (JP) 2023-07-05 EP disclosed
US-11578174-B2 Polyrotaxane, production method therefor, and optical composition containing said polyrotaxane TOKUYAMA CORPORATION (JP) 2023-02-14 US disclosed
US-20220137261-A1 OPTICAL ELEMENT, OPTICAL APPARATUS, IMAGING APPARATUS, AND COMPOUND CANON KABUSHIKI KAISHA (JP) 2022-05-05 US disclosed
EP-3269774-B1 METHOD FOR PRODUCING PHOTOCHROMIC CURED BODY TOKUYAMA CORP (JP) 2020-12-09 EP disclosed
EP-2497791-B1 METHOD FOR PRODUCING INTERNAL MOLD RELEASE AGENT FOR OPTICAL MATERIAL, INTERNAL MOLD RELEASE AGENT FOR OPTICAL MATERIAL, AND POLYMERIZABLE COMPOSITION INCLUDING THE SAME MITSUI CHEMICALS INC (JP) 2020-05-13 EP disclosed
US-20200071467-A1 Polyrotaxane, Production Method Therefor, and Optical Composition Containing said Polyrotaxane TOKUYAMA CORPORATION (JP) 2020-03-05 US disclosed
CN-105137508-B Compound, optical material and optical element used for optical elements 佳能株式会社 2019-11-08 CN disclosed
US-20010044555-A1 Thiol and sulfur-containing O-(meth)acrylate counpounds and use thereof KOBAYASHI SEIICHI (JP) 2001-11-22 US disclosed
US-6300464-B2 HIGH HEAT RESISTANCE AND REFRACTIVE INDEX, LOW SPECIFIC GRAVITY; POLYMERS CONTAINING THIO(EPOXY) AND AT LEAST ONE DISULFIDE BOND MITSUI CHEMICAL, INC. (JP) 2001-10-09 US disclosed
US-6265510-B1 OPTICS; LENSES MITSUI CHEMICALS, INC. (JP) 2001-07-24 US disclosed
US-20010002413-A1 Polymerizable composition MORIJIRI HIROYUKI (JP) 2001-05-31 US disclosed
US-6204311-B1 (THIO)EPOXY COMPOUND HAVING AT LEAST ONE INTRAMOLECULAR DISULFIDE BOND AND A CURING CATALYST. MITSUI CHEMICALS, INC. (JP) 2001-03-20 US disclosed
EP-0810210-B1 Thiol and sulfur-containing o-(meth)acrylate compounds and use thereof MITSUI CHEMICALS INC (JP) 2001-01-10 EP disclosed
US-6114485-A STARTING MATERIAL FOR A RESIN COMPOSITION USED IN OPTICAL APPLICATIONS SUCH AS A LENS MITSUI CHEMICALS, INC. (JP) 2000-09-05 US disclosed
EP-0942027-A2 A polymerizable composition Mitsui Chemicals, Inc. (JP) 1999-09-15 EP disclosed
US-5916987-A OPTICAL RESIN; LENSES MITSUI CHEMICALS, INC. (JP) 1999-06-29 US disclosed
EP-0810210-A2 Thiol and sulfur-containing o-(meth)acrylate compounds and use thereof MITSUI TOATSU CHEMICALS, INC. (JP) 1997-12-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260110823-A1 OPTICAL ELEMENT, OPTICAL APPARATUS, IMAGING APPARATUS, AND COMPOUND RAD51, PIEZO1, ZYX AKT1 2786/4885TGM2 3795/4885FFAR1 469/4885
US-20010044555-A1 Thiol and sulfur-containing O-(meth)acrylate counpounds and use thereof MSRB3, BHMT2, HBS1L AKT1 3758/4885TGM2 1453/4885FFAR1 3145/4885
US-12529822-B2 Optical element, optical apparatus, imaging apparatus, and compound RAD51, SEM1, PSMA3 AKT1 3709/4885TGM2 2976/4885FFAR1 707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.