Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | WHR1 | P49842 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263818 | 0.93 | ACACA (0.38) | ALDH1A1L3MBTL1ACACAKDM4EHSD17B10 | |
| SCHEMBL13219267 | 0.92 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1ACACAKDM4EHSD17B10 | |
| SCHEMBL7263814 | 0.84 | ACACA (0.33) | ALDH1A1L3MBTL1ACACAKDM4EHPGD | |
| SCHEMBL3701217 | 0.83 | ACACA (0.43) | ALDH1A1ACACAKDM4ECYP3A4HPGD | |
| SCHEMBL3207524 | 0.82 | ACHE (0.41) | ALDH1A1L3MBTL1KDM4EHSD17B10HPGD | |
| SCHEMBL3039685 | 0.81 | ACHE (0.40) | ALDH1A1L3MBTL1KDM4EHSD17B10HPGD | |
| SCHEMBL12022729 | 0.81 | ACHE (0.40) | ALDH1A1L3MBTL1KDM4EHSD17B10HPGD | |
| SCHEMBL7264850 | 0.80 | TP53 (0.32) | ALDH1A1L3MBTL1ACACAKDM4EHSD17B10 | |
| Methylene Chloride SCHEMBL3209457 | 0.79 | ACHE (0.39) | ALDH1A1L3MBTL1KDM4EHSD17B10HPGD | |
| Methylene Chloride SCHEMBL3037402 | 0.79 | ACHE (0.38) | ALDH1A1L3MBTL1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630597-B1 | Photochromic 6-aryl substituted 3H-naphtho(2, 1-b)pyran compounds, examples of which are naphthopyran compounds having a substituted aryl group at the number 6 carbon atom and certain substituents at the 3-position of the pyran ring | TRANSITIONS OPTICAL, INC. | 2003-10-07 | — | — | US | claimed |
| US-10758643-B2 | Mechanophoric medical product | AESCULAP AG (DE) | 2020-09-01 | — | — | US | disclosed |
| EP-3331581-B1 | MECHANOPHORIC MEDICAL PRODUKT | AESCULAP AG (DE) | 2020-07-08 | — | — | EP | disclosed |
| US-20190151502-A1 | Mechanophoric Medical Product | AESCULAP AG (DE) | 2019-05-23 | — | — | US | disclosed |
| EP-3331581-A1 | MECHANOPHORIC MEDICAL PRODUCT | Aesculap AG (DE) | 2018-06-13 | — | — | EP | disclosed |
| WO-2017025408-A1 | MECHANOPHORIC MEDICAL PRODUCT | AESCULAP AG (DE) | 2017-02-16 | — | — | WO | disclosed |
| US-6630597-B1 | Photochromic 6-aryl substituted 3H-naphtho(2, 1-b)pyran compounds, examples of which are naphthopyran compounds having a substituted aryl group at the number 6 carbon atom and certain substituents at the 3-position of the pyran ring | TRANSITIONS OPTICAL, INC. | 2003-10-07 | — | — | US | disclosed |