Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263818 | 0.86 | ACACA (0.38) | ACACAPIN1BACE1GPR84HPGD | |
| SCHEMBL7553115 | 0.85 | PDE4D (0.39) | HPGDKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL13219229 | 0.84 | GPR84 (0.36) | GPR84HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8311131 | 0.84 | EP300 (0.35) | HPGDKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7263189 | 0.83 | ALDH1A1 (0.38) | ACACAHPGDKDM4EALDH1A1KMT2A | |
| SCHEMBL7269803 | 0.82 | MAPT (0.33) | ACACABACE1GPR84KDM4ESMN1; SMN2 | |
| SCHEMBL7263814 | 0.81 | ACACA (0.33) | ACACAPIN1BACE1HPGDKDM4E | |
| SCHEMBL7270823 | 0.81 | GPR84 (0.37) | GPR84NPC1RAB9A | |
| SCHEMBL7528619 | 0.80 | GPR84 (0.48) | ACACAPIN1BACE1GPR84HPGD | |
| SCHEMBL5615321 | 0.79 | SMN1; SMN2 (0.43) | GPR84HPGDKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718754-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-103649789-B | Polarization photochromic article | TRANSITIONS OPTICAL, INC. (US) | 2016-03-16 | — | — | CN | disclosed |
| US-8545015-B2 | Polarizing photochromic articles | TRANSITIONS OPTICAL, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120120473-A1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2012-05-17 | — | — | US | disclosed |