Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270260 | 0.78 | RAB9A (0.55) | LMNAGAANPC1RAB9AMAPT | |
| SCHEMBL22853792 | 0.70 | LMNA (0.64) | LMNAGAANPC1RAB9AMAPT | |
| SCHEMBL9333371 | 0.68 | MAPT (0.61) | LMNANPC1RAB9AMAPTKDM4E | |
| SCHEMBL9904759 | 0.61 | TAAR1 (0.58) | GAANPC1RAB9AMAPTKDM4E | |
| SCHEMBL2914660 | 0.59 | TSHR (0.56) | LMNAGAAMAPTKDM4EALDH1A1 | |
| SCHEMBL3266109 | 0.58 | MAPT (0.53) | LMNAGAAMAPTKDM4EALDH1A1 | |
| SCHEMBL22805 | 0.58 | MAPT (0.46) | LMNAGAANPC1RAB9AMAPT | |
| SCHEMBL22628619 | 0.58 | RAB9A (0.65) | LMNAGAANPC1RAB9AMAPT | |
| SCHEMBL12038996 | 0.58 | TSHR (0.55) | LMNAGAAMAPTKDM4EALDH1A1 | |
| Pyrimethanil SCHEMBL20817 | 0.58 | SMN1; SMN2 (0.71) | LMNAGAANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | claimed |