Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262766 | 0.78 | MAPT (0.62) | RAB9AALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7263260 | 0.78 | LMNA (0.39) | RAB9AALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL15906854 | 0.75 | RAB9A (0.68) | RAB9AALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL14571425 | 0.73 | MAPT (0.77) | RAB9AALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL29633218 | 0.73 | MAPT (0.77) | RAB9AALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL29746447 | 0.73 | MAPT (0.69) | RAB9AALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL16296882 | 0.73 | MAPT (0.69) | RAB9AALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL16297243 | 0.73 | MAPT (0.64) | RAB9AALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL754259 | 0.72 | MAPT (1.00) | RAB9AALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL29633257 | 0.72 | MAPT (1.00) | RAB9AALDH1A1MAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | claimed |
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | disclosed |