Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 4/20 | 0.60 |
| ▸ | BLM | P54132 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | CASP3 | P42574 | 3/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755665 | 0.78 | MAPT (0.64) | MAPTSMN1; SMN2RAB9ALMNAHTT | |
| SCHEMBL5161058 | 0.78 | MAPT (0.64) | MAPTSMN1; SMN2RAB9ALMNAHTT | |
| SCHEMBL754259 | 0.76 | MAPT (1.00) | MAPTSMN1; SMN2RAB9ALMNAHTT | |
| SCHEMBL29633257 | 0.76 | MAPT (1.00) | MAPTSMN1; SMN2RAB9ALMNAHTT | |
| SCHEMBL17817052 | 0.76 | MAPT (0.53) | MAPTSMN1; SMN2RAB9ALMNAHTT | |
| SCHEMBL7264088 | 0.75 | MEN1 (0.44) | MAPTSMN1; SMN2RAB9ALMNAL3MBTL1 | |
| SCHEMBL8367064 | 0.75 | CDK4 (0.62) | MAPTSMN1; SMN2RAB9ALMNAHTT | |
| SCHEMBL28408126 | 0.74 | MAPT (0.96) | MAPTSMN1; SMN2RAB9ALMNAHTT | |
| SCHEMBL9334488 | 0.74 | MEN1 (0.61) | MAPTSMN1; SMN2RAB9ALMNAHTT | |
| SCHEMBL31312582 | 0.74 | POLB (0.45) | MAPTSMN1; SMN2RAB9ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3220163-A | — | — | None | — | — | JP | disclosed |
| EP-0443710-B1 | Benzoquinone antiallergy and antiinflammatory agents | PFIZER (US) | 1994-05-11 | — | — | EP | disclosed |
| US-5104874-A | Cyclooxygenase and lipoxygenase inhibitob | PFIZER INC. (US) | 1992-04-14 | — | — | US | disclosed |
| JP-H03220163-A | NEW BENZOQUINONE COMPOUND AND ITS COMPOSITION | PFIZER PHARMACEUT CO LTD | 1991-09-27 | — | — | JP | disclosed |
| EP-0443710-A1 | Benzoquinone antiallergy and antiinflammatory agents | PFIZER INC. (US) | 1991-08-28 | — | — | EP | disclosed |