SCHEMBL726391

SCHEMBL726391

CCCCCCCCCCCCCOC(=O)C(C(=O)OCCCCCCCCCCCCC)(C(=O)OC1CC(C)(C)N(C)C(C)(C)C1)C(CC)C(=O)OC1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GBA2 Q9HCG7 1/20 0.32
NAAA Q02083 1/20 0.31
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL726390 0.96 NAAA (0.31) GBA2NAAAEPHX1
SCHEMBL1434346 0.89 CYP2D6 (0.33)
SCHEMBL20637751 0.86 USP2 (0.35) GBA2NAAA
SCHEMBL725877 0.86 GAA (0.33) GBA2NAAAEPHX1
SCHEMBL725876 0.81 GAA (0.33) NAAAEPHX1
SCHEMBL9862841 0.81 ALDH1A1 (0.30)
SCHEMBL9839757 0.78 ALDH1A1 (0.30)
SCHEMBL8948961 0.77 NAAA (0.40) GBA2NAAAEPHX1
SCHEMBL8948960 0.77 HTR2C (0.47) NAAA
SCHEMBL8948993 0.77 HTR2C (0.47) NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4733898-B2 2011-07-27 JP claimed
US-20090312464-A1 Stabilizer mixtures GUGUMUS FRANCOIS 2009-12-17 US claimed
EP-1263855-B1 STABILIZER MIXTURES FOR POLYOLEFINS CIBA SC HOLDING AG (CH) 2008-03-12 EP claimed
EP-1077227-B1 Stabilizer mixtures CIBA SC HOLDING AG (CH) 2006-06-07 EP claimed
US-6869992-B2 Stabilizer mixtures for polyolefins CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-03-22 US claimed
US-20030153653-A1 Stabilizer mixtures CIBA SPECIALTY CHEMICALS CORP. 2003-08-14 US claimed
US-20030069337-A1 Stabilizer mixtures for polyolefins CIBA SPECIALTY CHEMICALS CORP. 2003-04-10 US claimed
EP-1263855-A1 STABILIZER MIXTURES FOR POLYOLEFINS Ciba SC Holding AG (CH) 2002-12-11 EP claimed
WO-2001062836-A1 STABILIZER MIXTURES FOR POLYOLEFINS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-30 WO claimed
EP-1077227-A1 Stabilizer mixtures Ciba SC Holding AG (CH) 2001-02-21 EP claimed
EP-3626772-A1 USE OF A MELAMINE BASED COMPOUND AND A HALS COMPOUND AS HEAT STABILIZER IN POLYMERS Borealis AG (AT) 2020-03-25 EP disclosed
EP-2758462-B1 STABILIZING OF ORGANIC MATERIAL WITH AMINO-TRIAZINE BASED MANNICH-COMPOUNDS BOREALIS AG (AT) 2018-03-07 EP disclosed
US-9546261-B2 Stabilizing of organic material with amino-triazine based mannich-compounds BOREALIS AG (AT) 2017-01-17 US disclosed
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds BOREALIS AG (AT) 2014-08-21 US disclosed
US-20090312464-A1 Stabilizer mixtures GUGUMUS FRANCOIS 2009-12-17 US disclosed
EP-1263855-A1 STABILIZER MIXTURES FOR POLYOLEFINS Ciba SC Holding AG (CH) 2002-12-11 EP disclosed
WO-2001062836-A1 STABILIZER MIXTURES FOR POLYOLEFINS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-30 WO disclosed
EP-1077227-A1 Stabilizer mixtures Ciba SC Holding AG (CH) 2001-02-21 EP disclosed
EP-1038912-A2 High molecular weight hindered hydrocarbyloxyamine stabilizers Ciba SC Holding AG (CH) 2000-09-27 EP disclosed
EP-0947546-A1 Blends of sterically hindered amines Ciba SC Holding AG (CH) 1999-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds PCNA, SOD1, UBE2M GBA2 939/4885NAAA 4213/4885EPHX1 4617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.