Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 2/20 | 0.45 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265951 | 0.84 | CTRC (0.58) | CTRCMEN1KMT2ATP53 | |
| SCHEMBL4368203 | 0.81 | SIRT2 (0.56) | CHEK2KMT2APARP1LMNAKDM4E | |
| SCHEMBL7266161 | 0.80 | KDM4E (0.52) | CHEK2MEN1KMT2APARP1MAP4K4 | |
| SCHEMBL6631157 | 0.80 | CHEK2 (0.54) | CHEK2CTRCPARP1MAP4K4LMNA | |
| SCHEMBL6068604 | 0.76 | PDE7A (0.50) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL7264531 | 0.71 | MEN1 (0.44) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL7909790 | 0.71 | MEN1 (0.44) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL7266039 | 0.71 | RHEB (0.50) | MEN1KMT2ALMNAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7264305 | 0.70 | MEN1 (0.43) | MEN1KMT2AALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL11772194 | 0.70 | ALDH1A1 (0.58) | MEN1KMT2ALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151529-B1 | 5-(AMINO OR SUBSTITUTED AMINO)-1,2,3-TRIAZOLES | MERCK & CO. INC. (US) | 1991-09-18 | — | — | EP | disclosed |
| US-4590201-A | ANTICOCCIDIAL AGENT FOR ANIMALS PARTICULARLY FOR POULTRY | MERCK & CO., INC. (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0151529-A2 | 5-(Amino or substituted amino)-1,2,3-triazoles | MERCK & CO. INC. (US) | 1985-08-14 | — | — | EP | disclosed |