Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568742 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7241026 | 0.81 | TSHR (0.49) | SMN1; SMN2HTTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7258049 | 0.80 | MAPT (0.40) | SMN1; SMN2LMNAMTNR1AMTNR1BADORA3 | |
| SCHEMBL498496 | 0.80 | CYP1B1 (0.42) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7261654 | 0.78 | CYP19A1 (0.41) | SMN1; SMN2LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL1974249 | 0.76 | TDP1 (0.49) | SMN1; SMN2LMNAHTTL3MBTL1KDM4E | |
| SCHEMBL7239834 | 0.76 | NPC1 (0.52) | SMN1; SMN2HTTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8865142 | 0.74 | NPC1 (0.50) | SMN1; SMN2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7241348 | 0.74 | KMT2A (0.45) | SMN1; SMN2HTTKDM4EALDH1A1MAPT | |
| SCHEMBL1680192 | 0.73 | ME2 (0.43) | SMN1; SMN2LMNAADORA3L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203888-A1 | Chromophores | WELLCOME TRUST LIMITED, THE (GB) | 2003-10-30 | — | — | US | disclosed |
| US-6419897-B1 | PORPHYRIN COMPOUNDS | ARIZONA BOARD OF REGENTS | 2002-07-16 | — | — | US | disclosed |
| US-6274729-B1 | PREVENT TISSUE DAMAGE | ARIZONA BOARD OF REGENTS | 2001-08-14 | — | — | US | disclosed |
| US-6207821-B1 | Long-wavelength electromagnetic radiation and photoprotective tumor localizing agents for diagnosis | ARIZONA BOARD OF REGENTS | 2001-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203888-A1 | Chromophores | HCCS, PPOX, HMBS | SMN1; SMN2 4747/4885LMNA 2646/4885MTNR1A 2928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.