Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498496 | 0.87 | CYP1B1 (0.42) | ALDH1A1SMN1; SMN2HPGDNPC1MAPT | |
| SCHEMBL3424113 | 0.82 | ALDH1A1 (0.42) | CYP19A1TDP1ALDH1A1SMN1; SMN2APP | |
| SCHEMBL1680192 | 0.81 | ME2 (0.43) | TDP1MAPK1ALDH1A1SMN1; SMN2APP | |
| SCHEMBL26095376 | 0.81 | ALDH1A1 (0.40) | CYP19A1TDP1ALDH1A1SMN1; SMN2APP | |
| SCHEMBL26096051 | 0.81 | ALDH1A1 (0.40) | CYP19A1TDP1ALDH1A1SMN1; SMN2APP | |
| Hydrochloric Acid SCHEMBL5534014 | 0.79 | ME2 (0.42) | TDP1MAPK1ALDH1A1SMN1; SMN2APP | |
| Hydrochloric Acid SCHEMBL15769036 | 0.78 | ME2 (0.41) | TDP1MAPK1ALDH1A1SMN1; SMN2APP | |
| SCHEMBL9429810 | 0.78 | ACHE (0.46) | TDP1MAPK1ALDH1A1SMN1; SMN2APP | |
| SCHEMBL7261920 | 0.77 | CYP19A1 (0.36) | CYP19A1TDP1ALDH1A1SMN1; SMN2APP | |
| SCHEMBL5015257 | 0.76 | CYP1A1 (0.39) | TDP1ALDH1A1SMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203888-A1 | Chromophores | WELLCOME TRUST LIMITED, THE (GB) | 2003-10-30 | — | — | US | disclosed |
| EP-1294726-A2 | IMPROVEMENTS IN AND RELATING TO CHROMOPHORES | Catalyst Biomedica Ltd (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000662-A1 | IMPROVEMENTS IN AND RELATING TO CHROMOPHORES | CATALYST BIOMEDICA LIMITED (GB) | 2002-01-03 | — | — | WO | disclosed |
| US-6183727-B1 | DETECTING A PATHOLOGY OR TARGET TISSUE BY ADMINISTERING A ZINC PHTHALOCYANINE DYES IMAGING MATERIAL AND EXPOSING TO RADIATION WITHOUT DAMAGING THE MAMMALIAN HOST | ARIZONA BOARD OF REGENTS | 2001-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203888-A1 | Chromophores | HCCS, PPOX, HMBS | CYP19A1 2552/4885NQO2 1308/4885TDP1 1478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.