Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822530 | 0.86 | EPHX1 (0.50) | HPGDEPHX1MEN1MAPTKMT2A | |
| SCHEMBL10521561 | 0.74 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL11460238 | 0.69 | HPGD (0.50) | HPGDEPHX1MEN1MAPTKMT2A | |
| SCHEMBL24363715 | 0.68 | HPGD (0.59) | HPGDEPHX1MAPTALDH1A1HSD17B10 | |
| SCHEMBL11670009 | 0.68 | HPGD (0.57) | HPGDEPHX1MEN1MAPTKMT2A | |
| SCHEMBL15355129 | 0.68 | MEN1 (0.50) | HPGDEPHX1MEN1MAPTKMT2A | |
| SCHEMBL6799750 | 0.67 | EPHX1 (0.63) | EPHX1MEN1KMT2AALDH1A1CTSK | |
| SCHEMBL28208913 | 0.66 | ALDH1A1 (0.49) | HPGDEPHX1MEN1MAPTKMT2A | |
| SCHEMBL9850876 | 0.66 | SOAT1 (0.42) | HPGDEPHX1 | |
| SCHEMBL27940250 | 0.66 | HPGD (0.54) | HPGDEPHX1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309841-A2 | Amino acid derivatives | MERCK PATENT GmbH (DE) | 1989-04-05 | — | — | EP | disclosed |
| EP-0264795-A2 | Amino acid derivatives | MERCK PATENT GmbH (DE) | 1988-04-27 | — | — | EP | disclosed |