Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983 | 0.72 | TRPA1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7403491 | 0.71 | TRPA1 (0.31) | — | |
| SCHEMBL433359 | 0.71 | TRPA1 (0.31) | — | |
| SCHEMBL14678109 | 0.69 | — | — | |
| Dimethyl Sulfoxide SCHEMBL8008395 | 0.64 | — | — | |
| SCHEMBL5851752 | 0.63 | — | — | |
| Diethylamine SCHEMBL6655360 | 0.62 | — | — | |
| SCHEMBL11846232 | 0.62 | ACHE (0.46) | — | |
| SCHEMBL27845556 | 0.60 | NOX1 (0.34) | F7F3DYRK1A | |
| SCHEMBL7793703 | 0.60 | TP53 (0.36) | F7F3DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-64000019-A | — | — | None | — | — | JP | disclosed |
| JP-3258721-A | — | — | None | — | — | JP | disclosed |
| US-5674488-A | Method for prevention and treatment of hyperchlolesterolemia by in vivo hydrogenation of cholesterol | REICH JOHN J (US) | 1997-10-07 | — | — | US | disclosed |
| EP-0278449-B1 | AGENT HAVING RENAL FUNCTION-IMPROVING EFFECT AND DIURETIC EFFECT AND THE USE OF A BENZOTHIAZEPIN DERIVATIVE CONTAINED THEREIN | TANABE SEIYAKU CO., LTD. (JP) | 1992-09-30 | — | — | EP | disclosed |
| EP-0246573-B1 | PHARMACEUTICAL COMPOSITION CONTAINING A 8-CHLOROBENZOTHIAZEPINE COMPOUND AND ITS USE | TANABE SEIYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| EP-0246573-B1 | PHARMACEUTICAL COMPOSITION CONTAINING A 8-CHLOROBENZOTHIAZEPINE COMPOUND AND ITS USE | TANABE SEIYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| EP-0250814-B1 | PROPHYLACTIC AND CURING COMPOSITION CONTAINING A 8-CHLOROBENZOTHIAZEPINE COMPOUND AND ITS USE | TANABE SEIYAKU CO., LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| EP-0250814-B1 | PROPHYLACTIC AND CURING COMPOSITION CONTAINING A 8-CHLOROBENZOTHIAZEPINE COMPOUND AND ITS USE | TANABE SEIYAKU CO., LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| JP-H03258721-A | PHARMACEUTICAL COMPOSITION | TANABE SEIYAKU CO LTD | 1991-11-19 | — | — | JP | disclosed |
| US-4822789-A | ADMINISTERING 2(4-METHOXYPHENYL)-3-ACETOXY-5- 2(DIMETHYLAMINO) ETHYL!-8-CHLORO-2,3-DYHYDRO-1,5-BENZOTHIAZEPIN-(5H)-ONE | TANABE SEIYAKU CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| JP-S6419-A | RENAL FUNCTION-IMPROVING AND DIURETIC AGENT | TANABE SEIYAKU CO LTD | 1989-01-05 | — | — | JP | disclosed |
| US-4786634-A | ADMINISTERING AN 8-CHLORO-1,5-BENZOTHIAZEPINE DERIVATIVE | Tanabe Seikyaku Co., Ltd. (JP) | 1988-11-22 | — | — | US | disclosed |
| US-4778791-A | INCREASING RATIO OF HIGH DENSITY LIPOPROTEINS | TANABE SEIYAKU CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0278449-A2 | Agent having renal function-improving effect and diuretic effect and the use of a benzothiazepin derivative contained therein | TANABE SEIYAKU CO., LTD. (JP) | 1988-08-17 | — | — | EP | disclosed |
| EP-0250814-A2 | Prophylactic and curing composition containing a 8-chlorobenzothiazepine compound and its use | TANABE SEIYAKU CO., LTD. (JP) | 1988-01-07 | — | — | EP | disclosed |
| EP-0250814-A2 | Prophylactic and curing composition containing a 8-chlorobenzothiazepine compound and its use | TANABE SEIYAKU CO., LTD. (JP) | 1988-01-07 | — | — | EP | disclosed |
| EP-0246573-A2 | Pharmaceutical composition containing a 8-chlorobenzothiazepine compound and its use | TANABE SEIYAKU CO., LTD. (JP) | 1987-11-25 | — | — | EP | disclosed |
| EP-0246573-A2 | Pharmaceutical composition containing a 8-chlorobenzothiazepine compound and its use | TANABE SEIYAKU CO., LTD. (JP) | 1987-11-25 | — | — | EP | disclosed |