Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611523 | 0.79 | PKM (0.33) | LMNASMN1; SMN2TSHR | |
| SCHEMBL10463947 | 0.77 | ALDH1A1 (0.40) | LMNASMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL8645010 | 0.77 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL10616070 | 0.76 | NSD2 (0.46) | LMNASMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL19095461 | 0.72 | MAPT (0.36) | LMNASMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL10465325 | 0.72 | SMN1; SMN2 (0.36) | LMNASMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL9663862 | 0.72 | ALDH1A1 (0.49) | LMNASMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL8642432 | 0.71 | ALDH1A1 (0.36) | LMNASMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL8642688 | 0.71 | GSK3B (0.40) | LMNASMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL519774 | 0.70 | NSD2 (0.47) | LMNASMN1; SMN2KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064414-A1 | TRICYCLIC COMPOUNDS USEFUL AS ANGIOTENSIN II AGONISTS | VICORE PHARMA AB. (SE) | 2003-08-07 | — | — | WO | disclosed |