SCHEMBL457828

SCHEMBL457828

Brc1cccc(Oc2cccc(Br)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.54
EGFR P00533 3/20 0.50
ALDH1A1 P00352 2/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
MITF O75030 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
GFER P55789 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NLRP1 Q9C000 1/20 0.46
NOD2 Q9HC29 1/20 0.46
ABCG2 Q9UNQ0 1/20 0.46
MAPK1 P28482 1/20 0.46
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KDR P35968 1/20 0.44
PGR P06401 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3842164 0.97 MAOB (0.52) MAOBEGFRALDH1A1KMT2AMEN1
SCHEMBL3839157 0.95 ALDH1A1 (0.54) MAOBEGFRALDH1A1KMT2AMEN1
SCHEMBL3838974 0.95 ALDH1A1 (0.54) MAOBEGFRALDH1A1KMT2AMEN1
SCHEMBL29530517 0.93 MAOB (0.48) MAOBEGFRALDH1A1KMT2AMEN1
SCHEMBL30020579 0.93 LTA4H (0.57) MAOBEGFRALDH1A1KMT2AMEN1
SCHEMBL3838956 0.93 SMN1; SMN2 (0.58) MAOBEGFRALDH1A1KMT2AMEN1
SCHEMBL5434 0.93 LTA4H (0.57) MAOBEGFRALDH1A1KMT2AMEN1
SCHEMBL30633275 0.91 MAOB (0.55) MAOBEGFRALDH1A1KMT2AMEN1
SCHEMBL7265752 0.91 MAOB (0.55) MAOBEGFRALDH1A1KMT2AMEN1
SCHEMBL20566087 0.91 MAOB (0.47) MAOBEGFRALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4948864-A Catalytic method for manufacturing aromatic polyester resin from aromatic diol, aromatic dibromide and carbon monoxide TOSOH CORPORATION (JP) 1990-08-14 US claimed
EP-0355840-A2 Method for manufacturing aromatic polyester resin Tosoh Corporation (JP) 1990-02-28 EP claimed
US-12565486-B2 Non-platinum metal complexes for excimer based single dopant white organic light emitting diodes ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2026-03-03 US disclosed
US-20260015335-A1 AMINE-SUBSTITUTED FLUORESCENT COMPOUNDS HUGHES HOWARD MED INST (US) 2026-01-15 US disclosed
US-20260001857-A1 FLUORINATED FLUORESCENT COMPOUNDS HUGHES HOWARD MED INST (US) 2026-01-01 US disclosed
US-20250282744-A1 RED-SHIFTED FLUOROPHORES HOWARD HUGHES MEDICAL INSTITUTE 2025-09-11 US disclosed
US-12344594-B2 Red-shifted fluorophores HOWARD HUGHES MEDICAL INSTITUTE (US) 2025-07-01 US disclosed
US-20240368124-A1 NON-PLATINUM METAL COMPLEXES FOR EXCIMER BASED SINGLE DOPANT WHITE ORGANIC LIGHT EMITTING DIODES UNIV ARIZONA STATE (US) 2024-11-07 US disclosed
US-20240360169-A1 BLUE AND NARROW BAND GREEN AND RED EMITTING METAL COMPLEXES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2024-10-31 US disclosed
CN-118679164-A Photodynamic therapy and diagnosis RMW曹氏集团有限公司 2024-09-20 CN disclosed
US-12043611-B2 Non-platinum metal complexes for excimer based single dopant white organic light emitting diodes ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-07-23 US disclosed
EP-0355840-A2 Method for manufacturing aromatic polyester resin Tosoh Corporation (JP) 1990-02-28 EP disclosed
EP-0347878-A2 Method for manufacturing polyamide resin Tosoh Corporation (JP) 1989-12-27 EP disclosed
EP-0135938-B1 PROCESS FOR PRODUCING AROMATIC POLYETHER KETONES AND POLYTHIOETHER KETONES MITSUBISHI KASEI CORPORATION (JP) 1988-06-22 EP disclosed
US-4707536-A Catalytic preparation of aromatic polyketone from phosgene and aromatic ether or sulfide MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1987-11-17 US disclosed
US-4661581-A REACTING AROMATIC ETHERS OR THIOETHERS WITH PHOSGENE IN AN APROTIC SOLVENT WITH GROUP 3 METAL HALIDE CATALYST MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1987-04-28 US disclosed
EP-0135938-A2 Process for producing aromatic polyether ketones and polythioether ketones MITSUBISHI KASEI CORPORATION (JP) 1985-04-03 EP disclosed
US-4447660-A Process for the isomerization of ortho-and para-bromophenols or the ethers thereof into meta-bromophenols and corresponding ethers PCUK PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1984-05-08 US disclosed
US-4042603-A SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE UBE INDUSTRIES, LTD. (JA) 1977-08-16 US disclosed
US-3939084-A Functional fluid compositions containing substituted pyrimidines MONSANTO COMPANY (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368124-A1 NON-PLATINUM METAL COMPLEXES FOR EXCIMER BASED SINGLE DOPANT WHITE ORGANIC LIGHT EMITTING DIODES RUVBL2, PDCD1LG2, PDCD1 MAOB 2518/4885EGFR 1710/4885ALDH1A1 3245/4885
US-12344594-B2 Red-shifted fluorophores TFEB, DDX21, CDC73 MAOB 2860/4885EGFR 2928/4885ALDH1A1 1847/4885
US-12043611-B2 Non-platinum metal complexes for excimer based single dopant white organic light emitting diodes RUVBL2, PDCD1LG2, PDCD1 MAOB 2518/4885EGFR 1710/4885ALDH1A1 3245/4885
US-20250282744-A1 RED-SHIFTED FLUOROPHORES TFEB, DDX21, CDC73 MAOB 2869/4885EGFR 2928/4885ALDH1A1 1850/4885
US-20240360169-A1 BLUE AND NARROW BAND GREEN AND RED EMITTING METAL COMPLEXES OCIAD2, OCIAD1, ORC3 MAOB 1955/4885EGFR 2209/4885ALDH1A1 1758/4885
US-20260001857-A1 FLUORINATED FLUORESCENT COMPOUNDS MSN, CHN2, EFHD2 MAOB 381/4885EGFR 1320/4885ALDH1A1 3618/4885
US-20260015335-A1 AMINE-SUBSTITUTED FLUORESCENT COMPOUNDS AOC2, H1-2, CHAT MAOB 109/4885EGFR 2298/4885ALDH1A1 2761/4885
US-12565486-B2 Non-platinum metal complexes for excimer based single dopant white organic light emitting diodes RUVBL2, RUVBL1, PDCD1LG2 MAOB 2238/4885EGFR 1056/4885ALDH1A1 3113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.