Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
| ▸ | ALOX5AP | P20292 | 15/20 | 0.53 |
| ▸ | FEN1 | P39748 | 15/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7190899 | 0.85 | ALOX5AP (0.55) | OPRM1OPRK1ALOX5APFEN1MMP3 | |
| SCHEMBL6630002 | 0.84 | ALOX5AP (0.57) | OPRM1OPRK1ALOX5APFEN1 | |
| SCHEMBL2280981 | 0.84 | ALOX5AP (0.54) | OPRM1OPRK1ALOX5APFEN1 | |
| SCHEMBL9426493 | 0.83 | OPRM1 (0.55) | OPRM1OPRK1ALOX5APFEN1MMP3 | |
| SCHEMBL7266847 | 0.82 | ALOX5AP (0.55) | OPRM1OPRK1ALOX5APFEN1MMP3 | |
| SCHEMBL6771873 | 0.82 | EDNRA (0.58) | OPRM1OPRK1ALOX5APFEN1KCNH2 | |
| SCHEMBL1968159 | 0.81 | ALOX5AP (0.59) | ALOX5APFEN1 | |
| SCHEMBL9426237 | 0.81 | HRH4 (0.54) | OPRM1OPRK1ALOX5APFEN1MMP3 | |
| SCHEMBL7261137 | 0.81 | SCN9A (0.55) | OPRM1OPRK1 | |
| SCHEMBL6628076 | 0.80 | ALOX5AP (0.59) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003101381-A2 | 1,2 DIAMIDO CYCLOALKYL SODIUM CHANNEL BLOCKERS | MERCK & CO., INC. (US) | 2003-12-11 | — | — | WO | disclosed |