Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 18/20 | 0.57 |
| ▸ | FEN1 | P39748 | 18/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266847 | 0.89 | ALOX5AP (0.55) | ALOX5APFEN1OPRM1OPRK1 | |
| SCHEMBL7190899 | 0.87 | ALOX5AP (0.55) | ALOX5APFEN1OPRM1OPRK1 | |
| SCHEMBL2280981 | 0.85 | ALOX5AP (0.54) | ALOX5APFEN1OPRM1OPRK1 | |
| SCHEMBL7266374 | 0.84 | OPRM1 (0.54) | ALOX5APFEN1OPRM1OPRK1 | |
| SCHEMBL6974699 | 0.83 | ALOX5AP (0.53) | ALOX5APFEN1OPRM1OPRK1 | |
| SCHEMBL890585 | 0.83 | ALOX5AP (0.65) | ALOX5APFEN1 | |
| SCHEMBL6771873 | 0.83 | EDNRA (0.58) | ALOX5APFEN1OPRM1OPRK1 | |
| SCHEMBL1968159 | 0.82 | ALOX5AP (0.59) | ALOX5APFEN1NSD2 | |
| Hydrochloric Acid SCHEMBL6175800 | 0.82 | ALOX5AP (0.64) | ALOX5APFEN1NSD2 | |
| SCHEMBL6628076 | 0.81 | ALOX5AP (0.59) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874629-B1 | ISOXAZOLINE, ISOTHIAZOLINE AND PYRAZOLINE FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003101381-A2 | 1,2 DIAMIDO CYCLOALKYL SODIUM CHANNEL BLOCKERS | MERCK & CO., INC. (US) | 2003-12-11 | — | — | WO | disclosed |
| US-5939418-A | ANTICOAGULANT | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-08-17 | — | — | US | disclosed |
| US-5411980-A | Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists | MERCK & CO., INC. (US) | 1995-05-02 | — | — | US | disclosed |