SCHEMBL7267181

SCHEMBL7267181

O=S(=O)(Nc1ccc(F)c([Ti])c1F)c1ccc2ccccc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
GLO1 Q04760 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
PLAU P00749 1/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TSHR P16473 1/20 0.47
RAD52 P43351 1/20 0.46
PKM P14618 2/20 0.46
PKLR P30613 1/20 0.46
PGR P06401 1/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KAT6A Q92794 2/20 0.45
PGAM1 P18669 1/20 0.45
KAT7 O95251 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
KCNH2 Q12809 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10013445 0.77 MEN1 (0.60) MEN1KMT2AGLO1TDP1PLAU
SCHEMBL17849571 0.77 KAT6A (0.59) MEN1KMT2AGLO1TDP1ATM
SCHEMBL20164063 0.76 MEN1 (0.44) MEN1KMT2AGLO1TDP1PLAU
SCHEMBL28327804 0.74 MEN1 (0.56) MEN1KMT2AGLO1TDP1PLAU
SCHEMBL9927441 0.73 FBP1 (0.56) MEN1KMT2AGLO1TDP1PLAU
SCHEMBL483125 0.73 MEN1 (0.43) MEN1KMT2AGLO1TDP1PLAU
SCHEMBL28326526 0.71 MEN1 (0.56) MEN1KMT2AGLO1TDP1PLAU
SCHEMBL9942077 0.71 RECQL (0.71) MEN1KMT2AGLO1TDP1PLAU
SCHEMBL3260752 0.71 MEN1 (0.62) MEN1KMT2AGLO1TDP1PLAU
SCHEMBL9942088 0.71 ATM (0.72) MEN1KMT2APLAUATMPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1341040-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 2003-09-03 EP disclosed